Optimization of carbon and energy utilization through differential translational efficiency

Microorganisms must regulate allocation of resources in nutrient-limited conditions. Here, the authors combine Ribo-seq, RNA-seq and TSS-seq to study resource allocation in the acetogen C. ljungdahlii, and show that dynamic regulation of translational efficiency of metabolic pathways is critical.

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Bibliographic Details
Main Authors: Mahmoud M. Al-Bassam, Ji-Nu Kim, Livia S. Zaramela, Benjamin P. Kellman, Cristal Zuniga, Jacob M. Wozniak, David J. Gonzalez, Karsten Zengler
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/f005e712f6dc4eaf8dc695c18a9d1010
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Summary:Microorganisms must regulate allocation of resources in nutrient-limited conditions. Here, the authors combine Ribo-seq, RNA-seq and TSS-seq to study resource allocation in the acetogen C. ljungdahlii, and show that dynamic regulation of translational efficiency of metabolic pathways is critical.