Optimization of carbon and energy utilization through differential translational efficiency

Microorganisms must regulate allocation of resources in nutrient-limited conditions. Here, the authors combine Ribo-seq, RNA-seq and TSS-seq to study resource allocation in the acetogen C. ljungdahlii, and show that dynamic regulation of translational efficiency of metabolic pathways is critical.

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Autores principales:	Mahmoud M. Al-Bassam, Ji-Nu Kim, Livia S. Zaramela, Benjamin P. Kellman, Cristal Zuniga, Jacob M. Wozniak, David J. Gonzalez, Karsten Zengler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f005e712f6dc4eaf8dc695c18a9d1010
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spelling	oai:doaj.org-article:f005e712f6dc4eaf8dc695c18a9d10102021-12-02T17:32:03ZOptimization of carbon and energy utilization through differential translational efficiency10.1038/s41467-018-06993-62041-1723https://doaj.org/article/f005e712f6dc4eaf8dc695c18a9d10102018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06993-6https://doaj.org/toc/2041-1723Microorganisms must regulate allocation of resources in nutrient-limited conditions. Here, the authors combine Ribo-seq, RNA-seq and TSS-seq to study resource allocation in the acetogen C. ljungdahlii, and show that dynamic regulation of translational efficiency of metabolic pathways is critical.Mahmoud M. Al-BassamJi-Nu KimLivia S. ZaramelaBenjamin P. KellmanCristal ZunigaJacob M. WozniakDavid J. GonzalezKarsten ZenglerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mahmoud M. Al-Bassam Ji-Nu Kim Livia S. Zaramela Benjamin P. Kellman Cristal Zuniga Jacob M. Wozniak David J. Gonzalez Karsten Zengler Optimization of carbon and energy utilization through differential translational efficiency
description	Microorganisms must regulate allocation of resources in nutrient-limited conditions. Here, the authors combine Ribo-seq, RNA-seq and TSS-seq to study resource allocation in the acetogen C. ljungdahlii, and show that dynamic regulation of translational efficiency of metabolic pathways is critical.
format	article
author	Mahmoud M. Al-Bassam Ji-Nu Kim Livia S. Zaramela Benjamin P. Kellman Cristal Zuniga Jacob M. Wozniak David J. Gonzalez Karsten Zengler
author_facet	Mahmoud M. Al-Bassam Ji-Nu Kim Livia S. Zaramela Benjamin P. Kellman Cristal Zuniga Jacob M. Wozniak David J. Gonzalez Karsten Zengler
author_sort	Mahmoud M. Al-Bassam
title	Optimization of carbon and energy utilization through differential translational efficiency
title_short	Optimization of carbon and energy utilization through differential translational efficiency
title_full	Optimization of carbon and energy utilization through differential translational efficiency
title_fullStr	Optimization of carbon and energy utilization through differential translational efficiency
title_full_unstemmed	Optimization of carbon and energy utilization through differential translational efficiency
title_sort	optimization of carbon and energy utilization through differential translational efficiency
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f005e712f6dc4eaf8dc695c18a9d1010
work_keys_str_mv	AT mahmoudmalbassam optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency AT jinukim optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency AT liviaszaramela optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency AT benjaminpkellman optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency AT cristalzuniga optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency AT jacobmwozniak optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency AT davidjgonzalez optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency AT karstenzengler optimizationofcarbonandenergyutilizationthroughdifferentialtranslationalefficiency
_version_	1718380466779717632

Optimization of carbon and energy utilization through differential translational efficiency

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