PP1A-mediated dephosphorylation positively regulates YAP2 activity.
<h4>Background</h4>The Hippo/MST1 signaling pathway plays an important role in the regulation of cell proliferation and apoptosis. As a major downstream target of the Hippo/MST1 pathway, YAP2 (Yes-associated protein 2) functions as a transcriptional cofactor that has been implicated in m...
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Auteurs principaux: | Pei Wang, Yujie Bai, Bangrong Song, Yadong Wang, Dong Liu, Yongqiang Lai, Xiaolin Bi, Zengqiang Yuan |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/f0069f76a112453e8bda58db9a72e770 |
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