Submandibular lipoblastoma: Case report of a rare tumor in childhood

Lipoblastoma is a rare, benign tumor usually occurring in childhood. It is essentially localized in the extremities and trunk, with few cases reported in the neck. We report the case of a 2-year-old girl with a rapidly enlarging, painless neck mass. Magnetic resonance imaging (MRI) revealed a 3-cm m...

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Autores principales: Olfa El Amine, Meyssa Belghith, Hasna Salhi, Aida Goucha, Amor Gamoudi
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Lenguaje:EN
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2018
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Acceso en línea:https://doaj.org/article/f02062b514d3423e8bcc661d23580d6d
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spelling oai:doaj.org-article:f02062b514d3423e8bcc661d23580d6d2021-12-02T17:07:47ZSubmandibular lipoblastoma: Case report of a rare tumor in childhood2231-07702249-446410.4103/ajm.AJM_81_17https://doaj.org/article/f02062b514d3423e8bcc661d23580d6d2018-04-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.AJM_81_17https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Lipoblastoma is a rare, benign tumor usually occurring in childhood. It is essentially localized in the extremities and trunk, with few cases reported in the neck. We report the case of a 2-year-old girl with a rapidly enlarging, painless neck mass. Magnetic resonance imaging (MRI) revealed a 3-cm mass in the right submandibular region. Review of literature, diagnostic methods, and genetics of lipomatous tumors are discussed. Complete surgical excision via a lateral cervical approach demonstrated a white soft tissue with an adherent ganglion. Histology and immunohistochemistry confirmed the diagnosis of lipoblastoma. Cervical lipoblastoma is rare, and typically asymptomatic, rarely causing nerve compression or airway obstruction. MRI can help identifying the lipomatous nature of the mass, but the findings can be inconsistent due to variable maturity of fat cells and the mesenchymal content of the tumor. Diagnosis is always based on pathological examination. Further chromosomal analysis is useful in differentiating lipoblastoma from liposarcoma. Complete surgical excision is the recommended treatment.Olfa El AmineMeyssa BelghithHasna SalhiAida GouchaAmor GamoudiThieme Medical and Scientific Publishers Pvt. Ltd.articlebenign tumorhead and neckimmunohistochemestrylipoblastomaliposarcomaMedicineRENAvicenna Journal of Medicine, Vol 8, Iss 02, Pp 55-57 (2018)
institution DOAJ
collection DOAJ
language EN
topic benign tumor
head and neck
immunohistochemestry
lipoblastoma
liposarcoma
Medicine
R
spellingShingle benign tumor
head and neck
immunohistochemestry
lipoblastoma
liposarcoma
Medicine
R
Olfa El Amine
Meyssa Belghith
Hasna Salhi
Aida Goucha
Amor Gamoudi
Submandibular lipoblastoma: Case report of a rare tumor in childhood
description Lipoblastoma is a rare, benign tumor usually occurring in childhood. It is essentially localized in the extremities and trunk, with few cases reported in the neck. We report the case of a 2-year-old girl with a rapidly enlarging, painless neck mass. Magnetic resonance imaging (MRI) revealed a 3-cm mass in the right submandibular region. Review of literature, diagnostic methods, and genetics of lipomatous tumors are discussed. Complete surgical excision via a lateral cervical approach demonstrated a white soft tissue with an adherent ganglion. Histology and immunohistochemistry confirmed the diagnosis of lipoblastoma. Cervical lipoblastoma is rare, and typically asymptomatic, rarely causing nerve compression or airway obstruction. MRI can help identifying the lipomatous nature of the mass, but the findings can be inconsistent due to variable maturity of fat cells and the mesenchymal content of the tumor. Diagnosis is always based on pathological examination. Further chromosomal analysis is useful in differentiating lipoblastoma from liposarcoma. Complete surgical excision is the recommended treatment.
format article
author Olfa El Amine
Meyssa Belghith
Hasna Salhi
Aida Goucha
Amor Gamoudi
author_facet Olfa El Amine
Meyssa Belghith
Hasna Salhi
Aida Goucha
Amor Gamoudi
author_sort Olfa El Amine
title Submandibular lipoblastoma: Case report of a rare tumor in childhood
title_short Submandibular lipoblastoma: Case report of a rare tumor in childhood
title_full Submandibular lipoblastoma: Case report of a rare tumor in childhood
title_fullStr Submandibular lipoblastoma: Case report of a rare tumor in childhood
title_full_unstemmed Submandibular lipoblastoma: Case report of a rare tumor in childhood
title_sort submandibular lipoblastoma: case report of a rare tumor in childhood
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate 2018
url https://doaj.org/article/f02062b514d3423e8bcc661d23580d6d
work_keys_str_mv AT olfaelamine submandibularlipoblastomacasereportofararetumorinchildhood
AT meyssabelghith submandibularlipoblastomacasereportofararetumorinchildhood
AT hasnasalhi submandibularlipoblastomacasereportofararetumorinchildhood
AT aidagoucha submandibularlipoblastomacasereportofararetumorinchildhood
AT amorgamoudi submandibularlipoblastomacasereportofararetumorinchildhood
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