Submandibular lipoblastoma: Case report of a rare tumor in childhood
Lipoblastoma is a rare, benign tumor usually occurring in childhood. It is essentially localized in the extremities and trunk, with few cases reported in the neck. We report the case of a 2-year-old girl with a rapidly enlarging, painless neck mass. Magnetic resonance imaging (MRI) revealed a 3-cm m...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2018
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oai:doaj.org-article:f02062b514d3423e8bcc661d23580d6d2021-12-02T17:07:47ZSubmandibular lipoblastoma: Case report of a rare tumor in childhood2231-07702249-446410.4103/ajm.AJM_81_17https://doaj.org/article/f02062b514d3423e8bcc661d23580d6d2018-04-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.AJM_81_17https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Lipoblastoma is a rare, benign tumor usually occurring in childhood. It is essentially localized in the extremities and trunk, with few cases reported in the neck. We report the case of a 2-year-old girl with a rapidly enlarging, painless neck mass. Magnetic resonance imaging (MRI) revealed a 3-cm mass in the right submandibular region. Review of literature, diagnostic methods, and genetics of lipomatous tumors are discussed. Complete surgical excision via a lateral cervical approach demonstrated a white soft tissue with an adherent ganglion. Histology and immunohistochemistry confirmed the diagnosis of lipoblastoma. Cervical lipoblastoma is rare, and typically asymptomatic, rarely causing nerve compression or airway obstruction. MRI can help identifying the lipomatous nature of the mass, but the findings can be inconsistent due to variable maturity of fat cells and the mesenchymal content of the tumor. Diagnosis is always based on pathological examination. Further chromosomal analysis is useful in differentiating lipoblastoma from liposarcoma. Complete surgical excision is the recommended treatment.Olfa El AmineMeyssa BelghithHasna SalhiAida GouchaAmor GamoudiThieme Medical and Scientific Publishers Pvt. Ltd.articlebenign tumorhead and neckimmunohistochemestrylipoblastomaliposarcomaMedicineRENAvicenna Journal of Medicine, Vol 8, Iss 02, Pp 55-57 (2018) |
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benign tumor head and neck immunohistochemestry lipoblastoma liposarcoma Medicine R |
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benign tumor head and neck immunohistochemestry lipoblastoma liposarcoma Medicine R Olfa El Amine Meyssa Belghith Hasna Salhi Aida Goucha Amor Gamoudi Submandibular lipoblastoma: Case report of a rare tumor in childhood |
description |
Lipoblastoma is a rare, benign tumor usually occurring in childhood. It is essentially localized in the extremities and trunk, with few cases reported in the neck. We report the case of a 2-year-old girl with a rapidly enlarging, painless neck mass. Magnetic resonance imaging (MRI) revealed a 3-cm mass in the right submandibular region. Review of literature, diagnostic methods, and genetics of lipomatous tumors are discussed. Complete surgical excision via a lateral cervical approach demonstrated a white soft tissue with an adherent ganglion. Histology and immunohistochemistry confirmed the diagnosis of lipoblastoma. Cervical lipoblastoma is rare, and typically asymptomatic, rarely causing nerve compression or airway obstruction. MRI can help identifying the lipomatous nature of the mass, but the findings can be inconsistent due to variable maturity of fat cells and the mesenchymal content of the tumor. Diagnosis is always based on pathological examination. Further chromosomal analysis is useful in differentiating lipoblastoma from liposarcoma. Complete surgical excision is the recommended treatment. |
format |
article |
author |
Olfa El Amine Meyssa Belghith Hasna Salhi Aida Goucha Amor Gamoudi |
author_facet |
Olfa El Amine Meyssa Belghith Hasna Salhi Aida Goucha Amor Gamoudi |
author_sort |
Olfa El Amine |
title |
Submandibular lipoblastoma: Case report of a rare tumor in childhood |
title_short |
Submandibular lipoblastoma: Case report of a rare tumor in childhood |
title_full |
Submandibular lipoblastoma: Case report of a rare tumor in childhood |
title_fullStr |
Submandibular lipoblastoma: Case report of a rare tumor in childhood |
title_full_unstemmed |
Submandibular lipoblastoma: Case report of a rare tumor in childhood |
title_sort |
submandibular lipoblastoma: case report of a rare tumor in childhood |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
publishDate |
2018 |
url |
https://doaj.org/article/f02062b514d3423e8bcc661d23580d6d |
work_keys_str_mv |
AT olfaelamine submandibularlipoblastomacasereportofararetumorinchildhood AT meyssabelghith submandibularlipoblastomacasereportofararetumorinchildhood AT hasnasalhi submandibularlipoblastomacasereportofararetumorinchildhood AT aidagoucha submandibularlipoblastomacasereportofararetumorinchildhood AT amorgamoudi submandibularlipoblastomacasereportofararetumorinchildhood |
_version_ |
1718381591482335232 |