Age-related macular degeneration: current treatments

Jean Pierre Hubschman, Shantan Reddy, Steven D SchwartzJules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USAPurpose: Although important progress has been made in understanding age-related macular degeneration (...

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Autores principales:	Jean Pierre Hubschman, Shantan Reddy, Steven D Schwartz
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f02871cc9c954a0b8fc8e46a71a1a84e
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spelling	oai:doaj.org-article:f02871cc9c954a0b8fc8e46a71a1a84e2021-12-02T04:35:45ZAge-related macular degeneration: current treatments1177-54671177-5483https://doaj.org/article/f02871cc9c954a0b8fc8e46a71a1a84e2009-01-01T00:00:00Zhttp://www.dovepress.com/age-related-macular-degeneration-current-treatments-a2770https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Jean Pierre Hubschman, Shantan Reddy, Steven D SchwartzJules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USAPurpose: Although important progress has been made in understanding age-related macular degeneration (AMD), management of the disease continues to be a challenge. AMD research has led to a widening of available treatment options and improved prognostic perspectives. This essay reviews these treatment options.Design: Interpretative essay.Methods: Literature review and interpretation.Results: Current treatments to preserve vision in patients with non-exudative AMD include antioxidant vitamins and mineral supplementations. Exudative AMD is currently most often treated monthly with anti-VEGF intra-vitreal injections. However, investigators are beginning to experiment with combination therapy and surgical approaches in an attempt to limit the number of treatment and reduce the financial burden on the health care system.Conclusion: By better understanding the basis and pathogenesis of AMD, newer therapies will continue to be developed that target specific pathways in patients with AMD, with the hoped for outcome of better management of the disease and improved visual acuity.Keywords: age-related macular degeneration, VEGF, photodynamic therapy, laser, surgery Jean Pierre HubschmanShantan ReddySteven D SchwartzDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 155-166 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Jean Pierre Hubschman Shantan Reddy Steven D Schwartz Age-related macular degeneration: current treatments
description	Jean Pierre Hubschman, Shantan Reddy, Steven D SchwartzJules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USAPurpose: Although important progress has been made in understanding age-related macular degeneration (AMD), management of the disease continues to be a challenge. AMD research has led to a widening of available treatment options and improved prognostic perspectives. This essay reviews these treatment options.Design: Interpretative essay.Methods: Literature review and interpretation.Results: Current treatments to preserve vision in patients with non-exudative AMD include antioxidant vitamins and mineral supplementations. Exudative AMD is currently most often treated monthly with anti-VEGF intra-vitreal injections. However, investigators are beginning to experiment with combination therapy and surgical approaches in an attempt to limit the number of treatment and reduce the financial burden on the health care system.Conclusion: By better understanding the basis and pathogenesis of AMD, newer therapies will continue to be developed that target specific pathways in patients with AMD, with the hoped for outcome of better management of the disease and improved visual acuity.Keywords: age-related macular degeneration, VEGF, photodynamic therapy, laser, surgery
format	article
author	Jean Pierre Hubschman Shantan Reddy Steven D Schwartz
author_facet	Jean Pierre Hubschman Shantan Reddy Steven D Schwartz
author_sort	Jean Pierre Hubschman
title	Age-related macular degeneration: current treatments
title_short	Age-related macular degeneration: current treatments
title_full	Age-related macular degeneration: current treatments
title_fullStr	Age-related macular degeneration: current treatments
title_full_unstemmed	Age-related macular degeneration: current treatments
title_sort	age-related macular degeneration: current treatments
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/f02871cc9c954a0b8fc8e46a71a1a84e
work_keys_str_mv	AT jeanpierrehubschman agerelatedmaculardegenerationcurrenttreatments AT shantanreddy agerelatedmaculardegenerationcurrenttreatments AT stevendschwartz agerelatedmaculardegenerationcurrenttreatments
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Age-related macular degeneration: current treatments

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