Direct asymmetric N-propargylation of indoles and carbazoles catalyzed by lithium SPINOL phosphate
Asymmetric functionalization of N–H bonds constitutes an important but less developed class of reactions. Here, the authors report the asymmetric direct N-propargylation of indoles and carbazoles with a lithium SPINOL phosphate as the chiral catalyst and shed light on the reaction mechanism.
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| Main Authors: | , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/f0297b5c324646a1b9b6c1c80de3145b |
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