Direct asymmetric N-propargylation of indoles and carbazoles catalyzed by lithium SPINOL phosphate

Asymmetric functionalization of N–H bonds constitutes an important but less developed class of reactions. Here, the authors report the asymmetric direct N-propargylation of indoles and carbazoles with a lithium SPINOL phosphate as the chiral catalyst and shed light on the reaction mechanism.

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Autores principales: Yingcheng Wang, Sheng Wang, Wenyu Shan, Zhihui Shao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f0297b5c324646a1b9b6c1c80de3145b
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