Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression
Abstract Knocking down delta-5-desaturase (D5D) by siRNA or shRNA is a promising strategy to achieve 8-hydroxyoctanoic acid (8-HOA) production for cancer inhibition. However, the RNAi-based strategy to stimulate 8-HOA is restricted due to endonucleases mediated physiological degradation and off-targ...
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Autores principales: | Harshit Shah, Lizhi Pang, Steven Qian, Venkatachalem Sathish |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/f03d085c41d4413e8a48848b2bcddc17 |
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