Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression

Abstract Knocking down delta-5-desaturase (D5D) by siRNA or shRNA is a promising strategy to achieve 8-hydroxyoctanoic acid (8-HOA) production for cancer inhibition. However, the RNAi-based strategy to stimulate 8-HOA is restricted due to endonucleases mediated physiological degradation and off-targ...

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Autores principales: Harshit Shah, Lizhi Pang, Steven Qian, Venkatachalem Sathish
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f03d085c41d4413e8a48848b2bcddc17
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