Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression
Abstract Knocking down delta-5-desaturase (D5D) by siRNA or shRNA is a promising strategy to achieve 8-hydroxyoctanoic acid (8-HOA) production for cancer inhibition. However, the RNAi-based strategy to stimulate 8-HOA is restricted due to endonucleases mediated physiological degradation and off-targ...
Enregistré dans:
Auteurs principaux: | Harshit Shah, Lizhi Pang, Steven Qian, Venkatachalem Sathish |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f03d085c41d4413e8a48848b2bcddc17 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Bispecific binder redirected lentiviral vector enables in vivo engineering of CAR-T cells
par: Barbara Savoldo, et autres
Publié: (2021) -
Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy
par: Hong-fen Guo, et autres
Publié: (2021) -
S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue
par: Sonali Jindal, et autres
Publié: (2020) -
Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity
par: Congcong Zhang, et autres
Publié: (2021) -
Emerging role of cell polarity proteins in breast cancer progression and metastasis
par: Chatterjee SJ, et autres
Publié: (2014)