Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)

Introduction Our aim was to compare in a prospective randomized study the safety, direct results and periprocedural data of ablation using an nMARQ catheter, a PVAC catheter used with the EnSite system, or a PVAC catheter only under fluoroscopy control. Material and methods One hundred two patients...

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Autores principales:	Edward Koźluk, Agnieszka Piątkowska, Dariusz Rodkiewicz, Michał Peller, Janusz Kochanowski, Grzegorz Opolski
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2018
Materias:	atrial fibrillation radiofrequency catheter ablation pulmonary vein isolation pvac catheter nmarq catheter Medicine R
Acceso en línea:	https://doaj.org/article/f0408e6756994fcfad4bf9151ca70450
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spelling	oai:doaj.org-article:f0408e6756994fcfad4bf9151ca704502021-12-02T16:58:24ZDirect results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)1734-19221896-915110.5114/aoms.2017.68054https://doaj.org/article/f0408e6756994fcfad4bf9151ca704502018-12-01T00:00:00Zhttps://www.archivesofmedicalscience.com/Direct-results-of-a-prospective-randomized-study-comparing-ablation-with-the-nMARQ,70408,0,2.htmlhttps://doaj.org/toc/1734-1922https://doaj.org/toc/1896-9151Introduction Our aim was to compare in a prospective randomized study the safety, direct results and periprocedural data of ablation using an nMARQ catheter, a PVAC catheter used with the EnSite system, or a PVAC catheter only under fluoroscopy control. Material and methods One hundred two patients (70 male, 57 ±11 years) with atrial fibrillation (AF) were prospectively randomized to: group 1 – ablation performed with an nMARQ catheter and the CARTO 3 system; group 2 – a PVAC catheter used with the EnSite system; group 3 – ablation with a PVAC catheter without a 3D system. Results Complete isolation of 400/402 pulmonary veins (PV) (99.5%). Linear ablation was performed in 23 patients in group 1 (small distance between lines isolating PV), in 3 patients in group 2, in 1 patient in group 3. The superior vena cava was isolated in 1 patient, 9 patients, and 9 patients respectively. Duration of fluoroscopy and dose area product were significantly smaller in group 1 (6.5 ±2.9 min/808.8 ±393.9 cGy/cm2 vs. 13.6 ±5.6 min/1662.6 ±677.8 cGy/cm2 and 18.8 ±7.6 min/2327.9 ±975.5 cGy/cm2; p < 0.001). Procedure duration was shorter in group 1 (82.9 ±18.8 min vs. 101.2 ±19.6 min, p < 0.001 and 99.8 ±20.8 min, NS). Contrast injection was necessary in 2 patients in group 1, in 8 patients in group 2 and in all patients in group 3. Because nMARQ is a thermocool catheter, the volume of fluid injection was significantly greater (2348.5 ±543.5 ml vs. 1077.9 ±280.5 ml and 1076.5 ±375.6 ml, p < 0.001). There were no periprocedural deaths. We observed no cardiac tamponade, neurological complications and no atrioesophageal fistula during follow-up. Conclusions The lowest radiological exposure was observed during ablation performed with an nMARQ catheter. 3D systems reduced fluoroscopy duration and the necessity of contrast injection. The nMARQ catheter requires injection of a large volume of fluid.Edward KoźlukAgnieszka PiątkowskaDariusz RodkiewiczMichał PellerJanusz KochanowskiGrzegorz OpolskiTermedia Publishing Housearticleatrial fibrillationradiofrequency catheter ablationpulmonary vein isolationpvac catheternmarq catheterradiofrequency catheter ablationpulmonary vein isolationnmarq catheterMedicineRENArchives of Medical Science, Vol 15, Iss 1, Pp 78-85 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	atrial fibrillation radiofrequency catheter ablation pulmonary vein isolation pvac catheter nmarq catheter radiofrequency catheter ablation pulmonary vein isolation nmarq catheter Medicine R
spellingShingle	atrial fibrillation radiofrequency catheter ablation pulmonary vein isolation pvac catheter nmarq catheter radiofrequency catheter ablation pulmonary vein isolation nmarq catheter Medicine R Edward Koźluk Agnieszka Piątkowska Dariusz Rodkiewicz Michał Peller Janusz Kochanowski Grzegorz Opolski Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)
description	Introduction Our aim was to compare in a prospective randomized study the safety, direct results and periprocedural data of ablation using an nMARQ catheter, a PVAC catheter used with the EnSite system, or a PVAC catheter only under fluoroscopy control. Material and methods One hundred two patients (70 male, 57 ±11 years) with atrial fibrillation (AF) were prospectively randomized to: group 1 – ablation performed with an nMARQ catheter and the CARTO 3 system; group 2 – a PVAC catheter used with the EnSite system; group 3 – ablation with a PVAC catheter without a 3D system. Results Complete isolation of 400/402 pulmonary veins (PV) (99.5%). Linear ablation was performed in 23 patients in group 1 (small distance between lines isolating PV), in 3 patients in group 2, in 1 patient in group 3. The superior vena cava was isolated in 1 patient, 9 patients, and 9 patients respectively. Duration of fluoroscopy and dose area product were significantly smaller in group 1 (6.5 ±2.9 min/808.8 ±393.9 cGy/cm2 vs. 13.6 ±5.6 min/1662.6 ±677.8 cGy/cm2 and 18.8 ±7.6 min/2327.9 ±975.5 cGy/cm2; p < 0.001). Procedure duration was shorter in group 1 (82.9 ±18.8 min vs. 101.2 ±19.6 min, p < 0.001 and 99.8 ±20.8 min, NS). Contrast injection was necessary in 2 patients in group 1, in 8 patients in group 2 and in all patients in group 3. Because nMARQ is a thermocool catheter, the volume of fluid injection was significantly greater (2348.5 ±543.5 ml vs. 1077.9 ±280.5 ml and 1076.5 ±375.6 ml, p < 0.001). There were no periprocedural deaths. We observed no cardiac tamponade, neurological complications and no atrioesophageal fistula during follow-up. Conclusions The lowest radiological exposure was observed during ablation performed with an nMARQ catheter. 3D systems reduced fluoroscopy duration and the necessity of contrast injection. The nMARQ catheter requires injection of a large volume of fluid.
format	article
author	Edward Koźluk Agnieszka Piątkowska Dariusz Rodkiewicz Michał Peller Janusz Kochanowski Grzegorz Opolski
author_facet	Edward Koźluk Agnieszka Piątkowska Dariusz Rodkiewicz Michał Peller Janusz Kochanowski Grzegorz Opolski
author_sort	Edward Koźluk
title	Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)
title_short	Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)
title_full	Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)
title_fullStr	Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)
title_full_unstemmed	Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)
title_sort	direct results of a prospective randomized study comparing ablation with the nmarq catheter and the pvac catheter used with and without a 3d system (maper 3d study)
publisher	Termedia Publishing House
publishDate	2018
url	https://doaj.org/article/f0408e6756994fcfad4bf9151ca70450
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Direct results of a prospective randomized study comparing ablation with the nMARQ catheter and the PVAC catheter used with and without a 3D system (MAPER 3D Study)

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