Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment

Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment

Size and charge can significantly affect delivery of therapeutic agents to tumours. Here, the authors report on nanoparticles optimised for delivery to the tumour which release smaller particles and change charge in the tumour microenvironment to optimise tumour penetration and cellular uptake.

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Autores principales: Xiangdong Xue, Yee Huang, Ruonan Bo, Bei Jia, Hao Wu, Ye Yuan, Zhongling Wang, Zhao Ma, Di Jing, Xiaobao Xu, Weimin Yu, Tzu-yin Lin, Yuanpei Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f043c185ba15462fb854e064b47ff772
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spelling oai:doaj.org-article:f043c185ba15462fb854e064b47ff7722021-12-02T17:33:17ZTrojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment10.1038/s41467-018-06093-52041-1723https://doaj.org/article/f043c185ba15462fb854e064b47ff7722018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06093-5https://doaj.org/toc/2041-1723Size and charge can significantly affect delivery of therapeutic agents to tumours. Here, the authors report on nanoparticles optimised for delivery to the tumour which release smaller particles and change charge in the tumour microenvironment to optimise tumour penetration and cellular uptake.Xiangdong XueYee HuangRuonan BoBei JiaHao WuYe YuanZhongling WangZhao MaDi JingXiaobao XuWeimin YuTzu-yin LinYuanpei LiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiangdong Xue
Yee Huang
Ruonan Bo
Bei Jia
Hao Wu
Ye Yuan
Zhongling Wang
Zhao Ma
Di Jing
Xiaobao Xu
Weimin Yu
Tzu-yin Lin
Yuanpei Li
Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment
description Size and charge can significantly affect delivery of therapeutic agents to tumours. Here, the authors report on nanoparticles optimised for delivery to the tumour which release smaller particles and change charge in the tumour microenvironment to optimise tumour penetration and cellular uptake.
format article
author Xiangdong Xue
Yee Huang
Ruonan Bo
Bei Jia
Hao Wu
Ye Yuan
Zhongling Wang
Zhao Ma
Di Jing
Xiaobao Xu
Weimin Yu
Tzu-yin Lin
Yuanpei Li
author_facet Xiangdong Xue
Yee Huang
Ruonan Bo
Bei Jia
Hao Wu
Ye Yuan
Zhongling Wang
Zhao Ma
Di Jing
Xiaobao Xu
Weimin Yu
Tzu-yin Lin
Yuanpei Li
author_sort Xiangdong Xue
title Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment
title_short Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment
title_full Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment
title_fullStr Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment
title_full_unstemmed Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment
title_sort trojan horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f043c185ba15462fb854e064b47ff772
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AT weiminyu trojanhorsenanotheranosticswithdualtransformabilityandmultifunctionalityforhighlyeffectivecancertreatment
AT tzuyinlin trojanhorsenanotheranosticswithdualtransformabilityandmultifunctionalityforhighlyeffectivecancertreatment
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