Unattached kinetochores drive their own capturing by sequestering a CLASP

Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattac...

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Autores principales: Caroline Kolenda, Jennifer Ortiz, Marina Pelzl, Sarina Norell, Verena Schmeiser, Johannes Lechner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f04529f23ed14fd98cef773f570ba4d7
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spelling oai:doaj.org-article:f04529f23ed14fd98cef773f570ba4d72021-12-02T14:39:07ZUnattached kinetochores drive their own capturing by sequestering a CLASP10.1038/s41467-018-03108-z2041-1723https://doaj.org/article/f04529f23ed14fd98cef773f570ba4d72018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03108-zhttps://doaj.org/toc/2041-1723Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattached KT.Caroline KolendaJennifer OrtizMarina PelzlSarina NorellVerena SchmeiserJohannes LechnerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Caroline Kolenda
Jennifer Ortiz
Marina Pelzl
Sarina Norell
Verena Schmeiser
Johannes Lechner
Unattached kinetochores drive their own capturing by sequestering a CLASP
description Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattached KT.
format article
author Caroline Kolenda
Jennifer Ortiz
Marina Pelzl
Sarina Norell
Verena Schmeiser
Johannes Lechner
author_facet Caroline Kolenda
Jennifer Ortiz
Marina Pelzl
Sarina Norell
Verena Schmeiser
Johannes Lechner
author_sort Caroline Kolenda
title Unattached kinetochores drive their own capturing by sequestering a CLASP
title_short Unattached kinetochores drive their own capturing by sequestering a CLASP
title_full Unattached kinetochores drive their own capturing by sequestering a CLASP
title_fullStr Unattached kinetochores drive their own capturing by sequestering a CLASP
title_full_unstemmed Unattached kinetochores drive their own capturing by sequestering a CLASP
title_sort unattached kinetochores drive their own capturing by sequestering a clasp
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f04529f23ed14fd98cef773f570ba4d7
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AT sarinanorell unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp
AT verenaschmeiser unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp
AT johanneslechner unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp
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