Unattached kinetochores drive their own capturing by sequestering a CLASP
Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattac...
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Nature Portfolio
2018
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oai:doaj.org-article:f04529f23ed14fd98cef773f570ba4d72021-12-02T14:39:07ZUnattached kinetochores drive their own capturing by sequestering a CLASP10.1038/s41467-018-03108-z2041-1723https://doaj.org/article/f04529f23ed14fd98cef773f570ba4d72018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03108-zhttps://doaj.org/toc/2041-1723Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattached KT.Caroline KolendaJennifer OrtizMarina PelzlSarina NorellVerena SchmeiserJohannes LechnerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q Caroline Kolenda Jennifer Ortiz Marina Pelzl Sarina Norell Verena Schmeiser Johannes Lechner Unattached kinetochores drive their own capturing by sequestering a CLASP |
description |
Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattached KT. |
format |
article |
author |
Caroline Kolenda Jennifer Ortiz Marina Pelzl Sarina Norell Verena Schmeiser Johannes Lechner |
author_facet |
Caroline Kolenda Jennifer Ortiz Marina Pelzl Sarina Norell Verena Schmeiser Johannes Lechner |
author_sort |
Caroline Kolenda |
title |
Unattached kinetochores drive their own capturing by sequestering a CLASP |
title_short |
Unattached kinetochores drive their own capturing by sequestering a CLASP |
title_full |
Unattached kinetochores drive their own capturing by sequestering a CLASP |
title_fullStr |
Unattached kinetochores drive their own capturing by sequestering a CLASP |
title_full_unstemmed |
Unattached kinetochores drive their own capturing by sequestering a CLASP |
title_sort |
unattached kinetochores drive their own capturing by sequestering a clasp |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/f04529f23ed14fd98cef773f570ba4d7 |
work_keys_str_mv |
AT carolinekolenda unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp AT jenniferortiz unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp AT marinapelzl unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp AT sarinanorell unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp AT verenaschmeiser unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp AT johanneslechner unattachedkinetochoresdrivetheirowncapturingbysequesteringaclasp |
_version_ |
1718390747406794752 |