The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage

The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage

Alternate splicing of mRNA precursors has been linked to tumor development. Here the authors reveal a role of the E3 ligase RNF113A in spliceosome regulation affecting cell survival upon DNA damage.

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Autores principales: Kateryna Shostak, Zheshen Jiang, Benoit Charloteaux, Alice Mayer, Yvette Habraken, Lars Tharun, Sebastian Klein, Xinyi Xu, Hong Quan Duong, Andrii Vislovukh, Pierre Close, Alexandra Florin, Florian Rambow, Jean-Christophe Marine, Reinhard Büttner, Alain Chariot
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f0459d053d834898b297f47efd32aaed
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spelling oai:doaj.org-article:f0459d053d834898b297f47efd32aaed2021-12-02T15:34:35ZThe X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage10.1038/s41467-020-15003-72041-1723https://doaj.org/article/f0459d053d834898b297f47efd32aaed2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15003-7https://doaj.org/toc/2041-1723Alternate splicing of mRNA precursors has been linked to tumor development. Here the authors reveal a role of the E3 ligase RNF113A in spliceosome regulation affecting cell survival upon DNA damage.Kateryna ShostakZheshen JiangBenoit CharloteauxAlice MayerYvette HabrakenLars TharunSebastian KleinXinyi XuHong Quan DuongAndrii VislovukhPierre CloseAlexandra FlorinFlorian RambowJean-Christophe MarineReinhard BüttnerAlain ChariotNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kateryna Shostak
Zheshen Jiang
Benoit Charloteaux
Alice Mayer
Yvette Habraken
Lars Tharun
Sebastian Klein
Xinyi Xu
Hong Quan Duong
Andrii Vislovukh
Pierre Close
Alexandra Florin
Florian Rambow
Jean-Christophe Marine
Reinhard Büttner
Alain Chariot
The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
description Alternate splicing of mRNA precursors has been linked to tumor development. Here the authors reveal a role of the E3 ligase RNF113A in spliceosome regulation affecting cell survival upon DNA damage.
format article
author Kateryna Shostak
Zheshen Jiang
Benoit Charloteaux
Alice Mayer
Yvette Habraken
Lars Tharun
Sebastian Klein
Xinyi Xu
Hong Quan Duong
Andrii Vislovukh
Pierre Close
Alexandra Florin
Florian Rambow
Jean-Christophe Marine
Reinhard Büttner
Alain Chariot
author_facet Kateryna Shostak
Zheshen Jiang
Benoit Charloteaux
Alice Mayer
Yvette Habraken
Lars Tharun
Sebastian Klein
Xinyi Xu
Hong Quan Duong
Andrii Vislovukh
Pierre Close
Alexandra Florin
Florian Rambow
Jean-Christophe Marine
Reinhard Büttner
Alain Chariot
author_sort Kateryna Shostak
title The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
title_short The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
title_full The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
title_fullStr The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
title_full_unstemmed The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
title_sort x-linked trichothiodystrophy-causing gene rnf113a links the spliceosome to cell survival upon dna damage
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f0459d053d834898b297f47efd32aaed
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