Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor

Abstract The formation of dentin and enamel matrix depends on reciprocal interactions between epithelial-mesenchymal cells. To assess the role of mitochondrial function in amelogenesis and dentinogenesis, we studied postnatal incisor development in K320E-TwinkleEpi mice. In these mice, a loss of mit...

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Autores principales: Thomas Imhof, Katharina Rosenblatt, Galyna Pryymachuk, Daniela Weiland, Nicolas Noetzel, James Deschner, Olivier R. Baris, Sammy Kimoloi, Manuel Koch, Rudolf J. Wiesner, Yüksel Korkmaz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f049116023de4f6289ee1a5fc2101949
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