Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients

The combination of chemotherapy and broad-spectrum antibiotics induces gut microbiota (GM) dysbiosis in acute myeloid leukaemia (AML) leading to additional complications. Here, the authors report the efficacy in GM restoration and safety of autologous faecal microbiota transfer in treated AML patien...

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Autores principales: Florent Malard, Anne Vekhoff, Simona Lapusan, Francoise Isnard, Evelyne D’incan-Corda, Jérôme Rey, Colombe Saillard, Xavier Thomas, Sophie Ducastelle-Lepretre, Etienne Paubelle, Marie-Virginie Larcher, Clément Rocher, Christian Recher, Suzanne Tavitian, Sarah Bertoli, Anne-Sophie Michallet, Lila Gilis, Pierre Peterlin, Patrice Chevallier, Stéphanie Nguyen, Emilie Plantamura, Lilia Boucinha, Cyrielle Gasc, Mauricette Michallet, Joel Dore, Ollivier Legrand, Mohamad Mohty
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f0565b9c6bfc48c0b52d42791181b41c
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spelling oai:doaj.org-article:f0565b9c6bfc48c0b52d42791181b41c2021-12-02T16:53:15ZGut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients10.1038/s41467-021-23376-62041-1723https://doaj.org/article/f0565b9c6bfc48c0b52d42791181b41c2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23376-6https://doaj.org/toc/2041-1723The combination of chemotherapy and broad-spectrum antibiotics induces gut microbiota (GM) dysbiosis in acute myeloid leukaemia (AML) leading to additional complications. Here, the authors report the efficacy in GM restoration and safety of autologous faecal microbiota transfer in treated AML patients in a phase II clinical trial.Florent MalardAnne VekhoffSimona LapusanFrancoise IsnardEvelyne D’incan-CordaJérôme ReyColombe SaillardXavier ThomasSophie Ducastelle-LepretreEtienne PaubelleMarie-Virginie LarcherClément RocherChristian RecherSuzanne TavitianSarah BertoliAnne-Sophie MichalletLila GilisPierre PeterlinPatrice ChevallierStéphanie NguyenEmilie PlantamuraLilia BoucinhaCyrielle GascMauricette MichalletJoel DoreOllivier LegrandMohamad MohtyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Florent Malard
Anne Vekhoff
Simona Lapusan
Francoise Isnard
Evelyne D’incan-Corda
Jérôme Rey
Colombe Saillard
Xavier Thomas
Sophie Ducastelle-Lepretre
Etienne Paubelle
Marie-Virginie Larcher
Clément Rocher
Christian Recher
Suzanne Tavitian
Sarah Bertoli
Anne-Sophie Michallet
Lila Gilis
Pierre Peterlin
Patrice Chevallier
Stéphanie Nguyen
Emilie Plantamura
Lilia Boucinha
Cyrielle Gasc
Mauricette Michallet
Joel Dore
Ollivier Legrand
Mohamad Mohty
Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
description The combination of chemotherapy and broad-spectrum antibiotics induces gut microbiota (GM) dysbiosis in acute myeloid leukaemia (AML) leading to additional complications. Here, the authors report the efficacy in GM restoration and safety of autologous faecal microbiota transfer in treated AML patients in a phase II clinical trial.
format article
author Florent Malard
Anne Vekhoff
Simona Lapusan
Francoise Isnard
Evelyne D’incan-Corda
Jérôme Rey
Colombe Saillard
Xavier Thomas
Sophie Ducastelle-Lepretre
Etienne Paubelle
Marie-Virginie Larcher
Clément Rocher
Christian Recher
Suzanne Tavitian
Sarah Bertoli
Anne-Sophie Michallet
Lila Gilis
Pierre Peterlin
Patrice Chevallier
Stéphanie Nguyen
Emilie Plantamura
Lilia Boucinha
Cyrielle Gasc
Mauricette Michallet
Joel Dore
Ollivier Legrand
Mohamad Mohty
author_facet Florent Malard
Anne Vekhoff
Simona Lapusan
Francoise Isnard
Evelyne D’incan-Corda
Jérôme Rey
Colombe Saillard
Xavier Thomas
Sophie Ducastelle-Lepretre
Etienne Paubelle
Marie-Virginie Larcher
Clément Rocher
Christian Recher
Suzanne Tavitian
Sarah Bertoli
Anne-Sophie Michallet
Lila Gilis
Pierre Peterlin
Patrice Chevallier
Stéphanie Nguyen
Emilie Plantamura
Lilia Boucinha
Cyrielle Gasc
Mauricette Michallet
Joel Dore
Ollivier Legrand
Mohamad Mohty
author_sort Florent Malard
title Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
title_short Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
title_full Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
title_fullStr Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
title_full_unstemmed Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
title_sort gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f0565b9c6bfc48c0b52d42791181b41c
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