Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow

Identifying and annotating functional elements in the human genome remains a challenging but important task. Here the authors propose a priority annotation score to rank identifications and suggest how proteogenomics evidence can be interpreted and what additional information substantiates protein-c...

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Autores principales:	James C. Wright, Jonathan Mudge, Hendrik Weisser, Mitra P. Barzine, Jose M. Gonzalez, Alvis Brazma, Jyoti S. Choudhary, Jennifer Harrow
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f06fc2c10cd544f0962bfeb9db43f5df
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spelling	oai:doaj.org-article:f06fc2c10cd544f0962bfeb9db43f5df2021-12-02T15:34:56ZImproving GENCODE reference gene annotation using a high-stringency proteogenomics workflow10.1038/ncomms117782041-1723https://doaj.org/article/f06fc2c10cd544f0962bfeb9db43f5df2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11778https://doaj.org/toc/2041-1723Identifying and annotating functional elements in the human genome remains a challenging but important task. Here the authors propose a priority annotation score to rank identifications and suggest how proteogenomics evidence can be interpreted and what additional information substantiates protein-coding potential for annotation.James C. WrightJonathan MudgeHendrik WeisserMitra P. BarzineJose M. GonzalezAlvis BrazmaJyoti S. ChoudharyJennifer HarrowNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q James C. Wright Jonathan Mudge Hendrik Weisser Mitra P. Barzine Jose M. Gonzalez Alvis Brazma Jyoti S. Choudhary Jennifer Harrow Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow
description	Identifying and annotating functional elements in the human genome remains a challenging but important task. Here the authors propose a priority annotation score to rank identifications and suggest how proteogenomics evidence can be interpreted and what additional information substantiates protein-coding potential for annotation.
format	article
author	James C. Wright Jonathan Mudge Hendrik Weisser Mitra P. Barzine Jose M. Gonzalez Alvis Brazma Jyoti S. Choudhary Jennifer Harrow
author_facet	James C. Wright Jonathan Mudge Hendrik Weisser Mitra P. Barzine Jose M. Gonzalez Alvis Brazma Jyoti S. Choudhary Jennifer Harrow
author_sort	James C. Wright
title	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow
title_short	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow
title_full	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow
title_fullStr	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow
title_full_unstemmed	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow
title_sort	improving gencode reference gene annotation using a high-stringency proteogenomics workflow
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f06fc2c10cd544f0962bfeb9db43f5df
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Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow

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