Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis

QR Code

Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are well-recognised as an extended disease spectrum. This study hypothesised that cortical hyperexcitability, an early pathophysiological abnormality in ALS, would distinguish cognitive phenotypes, as a surrogate marker o...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Smriti Agarwal, Elizabeth Highton-Williamson, Jashelle Caga, James Howells, Thanuja Dharmadasa, José M. Matamala, Yan Ma, Kazumoto Shibuya, John R. Hodges, Rebekah M. Ahmed, Steve Vucic, Matthew C. Kiernan
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/f078d7f7bedc4ed1b7dc8b9ca05c2cf6
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

The cortical signature of amyotrophic lateral sclerosis.
par: Federica Agosta, et autres
Publié: (2012)

Cortical thinning and clinical heterogeneity in amyotrophic lateral sclerosis.
par: Domenico Maria Mezzapesa, et autres
Publié: (2013)

Factors That Influence Non-Motor Impairment Across the ALS-FTD Spectrum: Impact of Phenotype, Sex, Age, Onset and Disease Stage
par: Emma M. Devenney, et autres
Publié: (2021)

Amyotrophic lateral sclerosis and frontotemporal degeneration
Publié: (2000)

Abnormal RNA stability in amyotrophic lateral sclerosis
par: E. M. Tank, et autres
Publié: (2018)

Current and emerging treatments for amyotrophic lateral sclerosis
par: Stefano Zoccolella, et autres
Publié: (2009)

Amyotrophic lateral sclerosis official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.
Publié: (2006)

The Role of Nucleocytoplasmic Transport Defects in Amyotrophic Lateral Sclerosis
par: Joni Vanneste, et autres
Publié: (2021)

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
par: Russell L. McLaughlin, et autres
Publié: (2017)

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia
par: Kelly L. Williams, et autres
Publié: (2016)

Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis.
par: Russell Lewis McLaughlin, et autres
Publié: (2010)

Platelet serotonin level predicts survival in amyotrophic lateral sclerosis.
par: Luc Dupuis, et autres
Publié: (2010)

γ' Fibrinogen as a Predictor of Survival in Amyotrophic Lateral Sclerosis
par: Ana Catarina Pronto-Laborinho, et autres
Publié: (2021)

Rare CYLD Variants in Chinese Patients With Amyotrophic Lateral Sclerosis
par: Xiaojing Gu, et autres
Publié: (2021)

Adherence to riluzole in patients with amyotrophic lateral sclerosis: an observational study
par: Introna A, et autres
Publié: (2018)

Aberrant enteric neuromuscular system and dysbiosis in amyotrophic lateral sclerosis
par: Yongguo Zhang, et autres
Publié: (2021)

Nutrient Effects on Motor Neurons and the Risk of Amyotrophic Lateral Sclerosis
par: Polina S. Goncharova, et autres
Publié: (2021)

Projected increase in amyotrophic lateral sclerosis from 2015 to 2040
par: Karissa C. Arthur, et autres
Publié: (2016)

Sleep disturbances in patients with amyotrophic lateral sclerosis: current perspectives
par: Boentert M
Publié: (2019)

Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery.
par: Katrina Gwinn, et autres
Publié: (2007)

AUTOLOGOUS STEM CELL TRANSPLANTATION AND IMMUNOMODULATION IN AMYOTROPHIC LATERAL SCLEROSIS
par: David Uriel Ayllón Álvarez, et autres
Publié: (2021)

Extracellular Vesicles as Innovative Treatment Strategy for Amyotrophic Lateral Sclerosis
par: Ke Wang, et autres
Publié: (2021)

Study protocol of RESCUE-ALS: A Phase 2, randomised, double-blind, placebo-controlled study in early symptomatic amyotrophic lateral sclerosis patients to assess bioenergetic catalysis with CNM-Au8 as a mechanism to slow disease progression
par: William Huynh, et autres
Publié: (2021)

Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated
par: Tanisha Singh, et autres
Publié: (2021)

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
par: Seshiru Nakazawa, et autres
Publié: (2016)

Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
par: Luca Muzio, et autres
Publié: (2020)

Corrigendum: γ′ Fibrinogen as a Predictor of Survival in Amyotrophic Lateral Sclerosis
par: Ana Catarina Pronto-Laborinho, et autres
Publié: (2021)

Amyotrophic lateral sclerosis: applications of stem cells &ndash; an update
par: Lidia Cova, et autres
Publié: (2010)

Longitudinal Quantitative MRI Evaluation of Muscle Involvement in Amyotrophic Lateral Sclerosis
par: Matteo Paoletti, et autres
Publié: (2021)

Palliative care for patients in the USA with amyotrophic lateral sclerosis: current challenges
par: Houseman G, et autres
Publié: (2015)

New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis
par: Frances Theunissen, et autres
Publié: (2021)

TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis.
par: Rita J Guerreiro, et autres
Publié: (2008)

Circadian regulation of human cortical excitability
par: Julien Q. M. Ly, et autres
Publié: (2016)

Predictors of survival in patients with amyotrophic lateral sclerosis: A large meta-analysis
par: Wei-Ming Su, et autres
Publié: (2021)

Alterations of the serum and CSF ferritin levels and the diagnosis and prognosis of amyotrophic lateral sclerosis
par: Parastou Paydarnia, et autres
Publié: (2021)

BiP Heterozigosity Aggravates Pathological Deterioration in Experimental Amyotrophic Lateral Sclerosis
par: Marta Gómez-Almería, et autres
Publié: (2021)

Dietary BMAA exposure in an amyotrophic lateral sclerosis cluster from southern France.
par: Estelle Masseret, et autres
Publié: (2013)

Amyotrophic Lateral Sclerosis associated FUS mutation shortens mitochondria and induces neurotoxicity
par: Tadashi Nakaya, et autres
Publié: (2018)

Amyotrophic lateral sclerosis (ALS) and the endocrine system: Are there any further ties to be explored?
par: Alexios-Fotios A. Mentis, et autres
Publié: (2021)

Amyotrophic lateral sclerosis and other motor neuron disorders official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases.
Publié: (2005)