High flavivirus structural plasticity demonstrated by a non-spherical morphological variant

Dengue (DENV) and Zika (ZIKV) viruses normally display as smooth spherical particles, while DENV can also become bumpy-surfaced, resulting in immune evasion. Here, Morrone et al. report DENV and ZIKV infectious club-shaped particles (clubSP) that display distinct antibody binding properties.

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Autores principales:	Seamus R. Morrone, Valerie S. Y. Chew, Xin-Ni Lim, Thiam-Seng Ng, Victor A. Kostyuchenko, Shuijun Zhang, Melissa Wirawan, Pau-Ling Chew, Jaime Lee, Joanne L. Tan, Jiaqi Wang, Ter Yong Tan, Jian Shi, Gavin Screaton, Marc C. Morais, Shee-Mei Lok
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f08301c050d845ffa06cdd50556aeafb
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spelling	oai:doaj.org-article:f08301c050d845ffa06cdd50556aeafb2021-12-02T17:39:52ZHigh flavivirus structural plasticity demonstrated by a non-spherical morphological variant10.1038/s41467-020-16925-y2041-1723https://doaj.org/article/f08301c050d845ffa06cdd50556aeafb2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16925-yhttps://doaj.org/toc/2041-1723Dengue (DENV) and Zika (ZIKV) viruses normally display as smooth spherical particles, while DENV can also become bumpy-surfaced, resulting in immune evasion. Here, Morrone et al. report DENV and ZIKV infectious club-shaped particles (clubSP) that display distinct antibody binding properties.Seamus R. MorroneValerie S. Y. ChewXin-Ni LimThiam-Seng NgVictor A. KostyuchenkoShuijun ZhangMelissa WirawanPau-Ling ChewJaime LeeJoanne L. TanJiaqi WangTer Yong TanJian ShiGavin ScreatonMarc C. MoraisShee-Mei LokNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Seamus R. Morrone Valerie S. Y. Chew Xin-Ni Lim Thiam-Seng Ng Victor A. Kostyuchenko Shuijun Zhang Melissa Wirawan Pau-Ling Chew Jaime Lee Joanne L. Tan Jiaqi Wang Ter Yong Tan Jian Shi Gavin Screaton Marc C. Morais Shee-Mei Lok High flavivirus structural plasticity demonstrated by a non-spherical morphological variant
description	Dengue (DENV) and Zika (ZIKV) viruses normally display as smooth spherical particles, while DENV can also become bumpy-surfaced, resulting in immune evasion. Here, Morrone et al. report DENV and ZIKV infectious club-shaped particles (clubSP) that display distinct antibody binding properties.
format	article
author	Seamus R. Morrone Valerie S. Y. Chew Xin-Ni Lim Thiam-Seng Ng Victor A. Kostyuchenko Shuijun Zhang Melissa Wirawan Pau-Ling Chew Jaime Lee Joanne L. Tan Jiaqi Wang Ter Yong Tan Jian Shi Gavin Screaton Marc C. Morais Shee-Mei Lok
author_facet	Seamus R. Morrone Valerie S. Y. Chew Xin-Ni Lim Thiam-Seng Ng Victor A. Kostyuchenko Shuijun Zhang Melissa Wirawan Pau-Ling Chew Jaime Lee Joanne L. Tan Jiaqi Wang Ter Yong Tan Jian Shi Gavin Screaton Marc C. Morais Shee-Mei Lok
author_sort	Seamus R. Morrone
title	High flavivirus structural plasticity demonstrated by a non-spherical morphological variant
title_short	High flavivirus structural plasticity demonstrated by a non-spherical morphological variant
title_full	High flavivirus structural plasticity demonstrated by a non-spherical morphological variant
title_fullStr	High flavivirus structural plasticity demonstrated by a non-spherical morphological variant
title_full_unstemmed	High flavivirus structural plasticity demonstrated by a non-spherical morphological variant
title_sort	high flavivirus structural plasticity demonstrated by a non-spherical morphological variant
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f08301c050d845ffa06cdd50556aeafb
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High flavivirus structural plasticity demonstrated by a non-spherical morphological variant

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