Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing

Near-infrared (NIR) fluorescent proteins (FPs) offer advantages for spectral multiplexing and deep-tissue imaging. Here the authors engineer a smaller NIR FP based on the unexplored cyanobacteriochrome photoreceptor and demonstrate its use in various applications in cell culture as well as whole-bod...

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Autores principales: Olena S. Oliinyk, Anton A. Shemetov, Sergei Pletnev, Daria M. Shcherbakova, Vladislav V. Verkhusha
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f084943922214d3cb7f030c01b38e997
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spelling oai:doaj.org-article:f084943922214d3cb7f030c01b38e9972021-12-02T14:39:18ZSmallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing10.1038/s41467-018-08050-82041-1723https://doaj.org/article/f084943922214d3cb7f030c01b38e9972019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08050-8https://doaj.org/toc/2041-1723Near-infrared (NIR) fluorescent proteins (FPs) offer advantages for spectral multiplexing and deep-tissue imaging. Here the authors engineer a smaller NIR FP based on the unexplored cyanobacteriochrome photoreceptor and demonstrate its use in various applications in cell culture as well as whole-body imaging in vivo in mice.Olena S. OliinykAnton A. ShemetovSergei PletnevDaria M. ShcherbakovaVladislav V. VerkhushaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Olena S. Oliinyk
Anton A. Shemetov
Sergei Pletnev
Daria M. Shcherbakova
Vladislav V. Verkhusha
Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
description Near-infrared (NIR) fluorescent proteins (FPs) offer advantages for spectral multiplexing and deep-tissue imaging. Here the authors engineer a smaller NIR FP based on the unexplored cyanobacteriochrome photoreceptor and demonstrate its use in various applications in cell culture as well as whole-body imaging in vivo in mice.
format article
author Olena S. Oliinyk
Anton A. Shemetov
Sergei Pletnev
Daria M. Shcherbakova
Vladislav V. Verkhusha
author_facet Olena S. Oliinyk
Anton A. Shemetov
Sergei Pletnev
Daria M. Shcherbakova
Vladislav V. Verkhusha
author_sort Olena S. Oliinyk
title Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
title_short Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
title_full Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
title_fullStr Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
title_full_unstemmed Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
title_sort smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f084943922214d3cb7f030c01b38e997
work_keys_str_mv AT olenasoliinyk smallestnearinfraredfluorescentproteinevolvedfromcyanobacteriochromeasversatiletagforspectralmultiplexing
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AT sergeipletnev smallestnearinfraredfluorescentproteinevolvedfromcyanobacteriochromeasversatiletagforspectralmultiplexing
AT dariamshcherbakova smallestnearinfraredfluorescentproteinevolvedfromcyanobacteriochromeasversatiletagforspectralmultiplexing
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