Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey

Jean-Philippe Nordmann1, Christophe Baudouin1, Jean-Paul Renard2, Philippe Denis3, Antoine Lafuma4, Caroline Laurendeau4, Viviane Jeanbat4, Gilles Berdeaux5,61H&ocirc;pital des Quinzes-Vingt, Paris, France; 2H&ocirc;pital du Val de Gr&acirc;ce, Paris, France; 3H&ocirc...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jean-Philippe Nordmann, Christophe Baudouin, Jean-Paul Renard, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f08f4b9291ca432bbbf9145042823a31
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f08f4b9291ca432bbbf9145042823a31
record_format	dspace
spelling	oai:doaj.org-article:f08f4b9291ca432bbbf9145042823a312021-12-02T03:49:57ZMeasurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey1177-54671177-5483https://doaj.org/article/f08f4b9291ca432bbbf9145042823a312010-07-01T00:00:00Zhttp://www.dovepress.com/measurement-of-treatment-compliance-using-a-medical-device-for-glaucom-a4879https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Jean-Philippe Nordmann1, Christophe Baudouin1, Jean-Paul Renard2, Philippe Denis3, Antoine Lafuma4, Caroline Laurendeau4, Viviane Jeanbat4, Gilles Berdeaux5,61H&ocirc;pital des Quinzes-Vingt, Paris, France; 2H&ocirc;pital du Val de Gr&acirc;ce, Paris, France; 3H&ocirc;pital Edouard Herriot, Lyon, France; 4Cemka, Bourg-la-Reine, France; 5Alcon France, Rueil-Malmaison, France; 6Conservatoire National des Arts et M&eacute;tiers, Paris, FranceObjective: To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP).Methods: A computerized device (Travalert&reg;) that recorded daily instillation times and eye-drop counts was given for 3 months. Patients were declared compliant when at least 2 drops were instilled per day. Compliance rates were calculated for weekdays and weekends, separately, over 8 consecutive weeks. A principal components analysis (PCA) was followed by an ascendant hierarchical classification (AHC) to identify compliance groups.Results: 140 patients were recruited (mean age 65.5 years; 51.8% female) of whom 83.6% had primary open-angle glaucoma with mean IOP 23.9 mmHg before Travalert&reg; use. 60.7% were treated with DuoTrav&reg; (travoprost timolol fixed combination) and 39.3% with &shy;travoprost. The PCA identified two axes (compliance and treatment weeks). The AHC identified 3 &shy;compliance groups: &lsquo;high&rsquo; (56.6%, approx. 80% compliance), &lsquo;medium&rsquo; (21.2%, approx. 50% compliance), and &lsquo;low&rsquo; (22.1%, approx. 20% compliance). Demographics and glaucoma parameters did not predict low compliance. Final mean IOP was 16.1 mmHg, but higher in the low compliance group (17.7 mmHg, P = 0.02).Conclusions: Compliance measurement by a medical device showed compliance rates &lt;80% by 50% (approx.) of patients, significantly impacting IOP control. No demographic or glaucoma variable was associated with low compliance.Keywords: glaucoma, compliance, efficacy, intraocular pressure control Jean-Philippe NordmannChristophe BaudouinJean-Paul Renardet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 731-739 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Jean-Philippe Nordmann Christophe Baudouin Jean-Paul Renard et al Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
description	Jean-Philippe Nordmann1, Christophe Baudouin1, Jean-Paul Renard2, Philippe Denis3, Antoine Lafuma4, Caroline Laurendeau4, Viviane Jeanbat4, Gilles Berdeaux5,61H&ocirc;pital des Quinzes-Vingt, Paris, France; 2H&ocirc;pital du Val de Gr&acirc;ce, Paris, France; 3H&ocirc;pital Edouard Herriot, Lyon, France; 4Cemka, Bourg-la-Reine, France; 5Alcon France, Rueil-Malmaison, France; 6Conservatoire National des Arts et M&eacute;tiers, Paris, FranceObjective: To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP).Methods: A computerized device (Travalert&reg;) that recorded daily instillation times and eye-drop counts was given for 3 months. Patients were declared compliant when at least 2 drops were instilled per day. Compliance rates were calculated for weekdays and weekends, separately, over 8 consecutive weeks. A principal components analysis (PCA) was followed by an ascendant hierarchical classification (AHC) to identify compliance groups.Results: 140 patients were recruited (mean age 65.5 years; 51.8% female) of whom 83.6% had primary open-angle glaucoma with mean IOP 23.9 mmHg before Travalert&reg; use. 60.7% were treated with DuoTrav&reg; (travoprost timolol fixed combination) and 39.3% with &shy;travoprost. The PCA identified two axes (compliance and treatment weeks). The AHC identified 3 &shy;compliance groups: &lsquo;high&rsquo; (56.6%, approx. 80% compliance), &lsquo;medium&rsquo; (21.2%, approx. 50% compliance), and &lsquo;low&rsquo; (22.1%, approx. 20% compliance). Demographics and glaucoma parameters did not predict low compliance. Final mean IOP was 16.1 mmHg, but higher in the low compliance group (17.7 mmHg, P = 0.02).Conclusions: Compliance measurement by a medical device showed compliance rates &lt;80% by 50% (approx.) of patients, significantly impacting IOP control. No demographic or glaucoma variable was associated with low compliance.Keywords: glaucoma, compliance, efficacy, intraocular pressure control
format	article
author	Jean-Philippe Nordmann Christophe Baudouin Jean-Paul Renard et al
author_facet	Jean-Philippe Nordmann Christophe Baudouin Jean-Paul Renard et al
author_sort	Jean-Philippe Nordmann
title	Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
title_short	Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
title_full	Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
title_fullStr	Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
title_full_unstemmed	Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
title_sort	measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/f08f4b9291ca432bbbf9145042823a31
work_keys_str_mv	AT jeanphilippenordmann measurementoftreatmentcomplianceusingamedicaldeviceforglaucomapatientsassociatedwithintraocularpressurecontrolasurvey AT christophebaudouin measurementoftreatmentcomplianceusingamedicaldeviceforglaucomapatientsassociatedwithintraocularpressurecontrolasurvey AT jeanpaulrenard measurementoftreatmentcomplianceusingamedicaldeviceforglaucomapatientsassociatedwithintraocularpressurecontrolasurvey AT etal measurementoftreatmentcomplianceusingamedicaldeviceforglaucomapatientsassociatedwithintraocularpressurecontrolasurvey
_version_	1718401621392621568

Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey

Ejemplares similares