Biomarker discovery by integrated joint non-negative matrix factorization and pathway signature analyses

Abstract Predictive biomarkers are important for selecting appropriate patients for particular treatments. Comprehensive genomic, transcriptomic, and pharmacological data provide clues for understanding relationships between biomarkers and drugs. However, it is still difficult to mine biologically m...

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Autores principales: Naoya Fujita, Shinji Mizuarai, Katsuhiko Murakami, Kenta Nakai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f091510bcc004541819476ef898e5bff
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