Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma

Thorsteinn S Arnljots,1 Mario A Economou2,3 1Anterior Segment Department, St. Erik Eye Hospital, Stockholm, Sweden; 2Division of Ophthalmology and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; 3Department of Ophthalmology, Sophiahemmet Hospital, Stockholm, Sw...

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Autores principales:	Arnljots TS, Economou MA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	migs istent inject kahook dual blade glaucoma surgery goniotomy Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f0967cb6543540568e4fc7111cde0e64
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spelling	oai:doaj.org-article:f0967cb6543540568e4fc7111cde0e642021-12-02T14:14:47ZKahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma1177-5483https://doaj.org/article/f0967cb6543540568e4fc7111cde0e642021-02-01T00:00:00Zhttps://www.dovepress.com/kahook-dual-blade-goniotomy-vs-istent-inject-long-term-results-in-pati-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Thorsteinn S Arnljots,1 Mario A Economou2,3 1Anterior Segment Department, St. Erik Eye Hospital, Stockholm, Sweden; 2Division of Ophthalmology and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; 3Department of Ophthalmology, Sophiahemmet Hospital, Stockholm, SwedenCorrespondence: Thorsteinn S Arnljots Sankt Eriks Ögonsjukhus, Eugeniavägen 12, Solna, Stockholm, 171 64 Tel +46-8-672 30 63Email thorsteinn.snaebjornsson-arnljots@sll.sePurpose: Efficacy and safety evaluation of Kahook Dual Blade (KDB) goniotomy vs iStent inject implantation.Materials and Methods: Retrospective study in patients that underwent goniotomy with KDB or iStent inject implantation, stand-alone or combined with cataract surgery. Main outcome parameters were intraocular pressure (IOP), number of glaucoma medications, proportion of eyes achieving > 20% IOP reduction and number of eyes with postoperative IOP < 19 mmHg at last follow-up.Results: A total of 29 patients (30 eyes) were included in the iStent inject group and 30 patients (32 eyes) in the KDB group. Mean follow-ups were 20.9± 6.5 (KDB-alone) to 29.5± 7.6 (phaco-iStent inject) months. Pre- and post-operative IOPs were 22.2± 5.8 mmHg and 15.9± 4.3 mmHg (P=0.004) in the KDB-alone, 24.2± 6.8 mmHg and 16.2± 6.7 mmHg (P=0.001) in the phaco-KDB, 20.6± 5.4 mmHg and 20.9± 6.8 mmHg (P=0.598) in the iStent inject-alone as well as 20.9± 5.5 mmHg and 15.6± 3.4 mmHg (P=0.003) in the phaco-iStent inject subgroups. No major complications occurred.Conclusion: All KDB and iStent subgroups except the stand-alone iStent inject subgroup showed a clinically significant IOP-lowering effect as a stand-alone procedure or combined with cataract surgery. Goniotomy with KDB in this setting seems to offer an advantageous IOP reduction compared to iStent inject.Keywords: MIGS, iStent inject, Kahook Dual Blade, glaucoma surgery, goniotomyArnljots TSEconomou MADove Medical Pressarticlemigsistent injectkahook dual bladeglaucoma surgerygoniotomyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 541-550 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	migs istent inject kahook dual blade glaucoma surgery goniotomy Ophthalmology RE1-994
spellingShingle	migs istent inject kahook dual blade glaucoma surgery goniotomy Ophthalmology RE1-994 Arnljots TS Economou MA Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma
description	Thorsteinn S Arnljots,1 Mario A Economou2,3 1Anterior Segment Department, St. Erik Eye Hospital, Stockholm, Sweden; 2Division of Ophthalmology and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; 3Department of Ophthalmology, Sophiahemmet Hospital, Stockholm, SwedenCorrespondence: Thorsteinn S Arnljots Sankt Eriks Ögonsjukhus, Eugeniavägen 12, Solna, Stockholm, 171 64 Tel +46-8-672 30 63Email thorsteinn.snaebjornsson-arnljots@sll.sePurpose: Efficacy and safety evaluation of Kahook Dual Blade (KDB) goniotomy vs iStent inject implantation.Materials and Methods: Retrospective study in patients that underwent goniotomy with KDB or iStent inject implantation, stand-alone or combined with cataract surgery. Main outcome parameters were intraocular pressure (IOP), number of glaucoma medications, proportion of eyes achieving > 20% IOP reduction and number of eyes with postoperative IOP < 19 mmHg at last follow-up.Results: A total of 29 patients (30 eyes) were included in the iStent inject group and 30 patients (32 eyes) in the KDB group. Mean follow-ups were 20.9± 6.5 (KDB-alone) to 29.5± 7.6 (phaco-iStent inject) months. Pre- and post-operative IOPs were 22.2± 5.8 mmHg and 15.9± 4.3 mmHg (P=0.004) in the KDB-alone, 24.2± 6.8 mmHg and 16.2± 6.7 mmHg (P=0.001) in the phaco-KDB, 20.6± 5.4 mmHg and 20.9± 6.8 mmHg (P=0.598) in the iStent inject-alone as well as 20.9± 5.5 mmHg and 15.6± 3.4 mmHg (P=0.003) in the phaco-iStent inject subgroups. No major complications occurred.Conclusion: All KDB and iStent subgroups except the stand-alone iStent inject subgroup showed a clinically significant IOP-lowering effect as a stand-alone procedure or combined with cataract surgery. Goniotomy with KDB in this setting seems to offer an advantageous IOP reduction compared to iStent inject.Keywords: MIGS, iStent inject, Kahook Dual Blade, glaucoma surgery, goniotomy
format	article
author	Arnljots TS Economou MA
author_facet	Arnljots TS Economou MA
author_sort	Arnljots TS
title	Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma
title_short	Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma
title_full	Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma
title_fullStr	Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma
title_full_unstemmed	Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma
title_sort	kahook dual blade goniotomy vs istent inject: long-term results in patients with open-angle glaucoma
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/f0967cb6543540568e4fc7111cde0e64
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Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma

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