Temporal bias in case-control design: preventing reliable predictions of the future

One of the primary tools that researchers use to predict risk is the case-control study. Here, the authors identify a flaw, temporal bias, that is specific to and uniquely associated with these studies that occurs when the study period is not representative of the data that clinicians have during th...

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Autores principales:	William Yuan, Brett K. Beaulieu-Jones, Kun-Hsing Yu, Scott L. Lipnick, Nathan Palmer, Joseph Loscalzo, Tianxi Cai, Isaac S. Kohane
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f09efdb3737c425a8e69b209f85bbec0
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spelling	oai:doaj.org-article:f09efdb3737c425a8e69b209f85bbec02021-12-02T14:03:40ZTemporal bias in case-control design: preventing reliable predictions of the future10.1038/s41467-021-21390-22041-1723https://doaj.org/article/f09efdb3737c425a8e69b209f85bbec02021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21390-2https://doaj.org/toc/2041-1723One of the primary tools that researchers use to predict risk is the case-control study. Here, the authors identify a flaw, temporal bias, that is specific to and uniquely associated with these studies that occurs when the study period is not representative of the data that clinicians have during the diagnostic process, undermining the validity of predictions.William YuanBrett K. Beaulieu-JonesKun-Hsing YuScott L. LipnickNathan PalmerJoseph LoscalzoTianxi CaiIsaac S. KohaneNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q William Yuan Brett K. Beaulieu-Jones Kun-Hsing Yu Scott L. Lipnick Nathan Palmer Joseph Loscalzo Tianxi Cai Isaac S. Kohane Temporal bias in case-control design: preventing reliable predictions of the future
description	One of the primary tools that researchers use to predict risk is the case-control study. Here, the authors identify a flaw, temporal bias, that is specific to and uniquely associated with these studies that occurs when the study period is not representative of the data that clinicians have during the diagnostic process, undermining the validity of predictions.
format	article
author	William Yuan Brett K. Beaulieu-Jones Kun-Hsing Yu Scott L. Lipnick Nathan Palmer Joseph Loscalzo Tianxi Cai Isaac S. Kohane
author_facet	William Yuan Brett K. Beaulieu-Jones Kun-Hsing Yu Scott L. Lipnick Nathan Palmer Joseph Loscalzo Tianxi Cai Isaac S. Kohane
author_sort	William Yuan
title	Temporal bias in case-control design: preventing reliable predictions of the future
title_short	Temporal bias in case-control design: preventing reliable predictions of the future
title_full	Temporal bias in case-control design: preventing reliable predictions of the future
title_fullStr	Temporal bias in case-control design: preventing reliable predictions of the future
title_full_unstemmed	Temporal bias in case-control design: preventing reliable predictions of the future
title_sort	temporal bias in case-control design: preventing reliable predictions of the future
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f09efdb3737c425a8e69b209f85bbec0
work_keys_str_mv	AT williamyuan temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture AT brettkbeaulieujones temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture AT kunhsingyu temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture AT scottllipnick temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture AT nathanpalmer temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture AT josephloscalzo temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture AT tianxicai temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture AT isaacskohane temporalbiasincasecontroldesignpreventingreliablepredictionsofthefuture
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Temporal bias in case-control design: preventing reliable predictions of the future

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