Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD

Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in individuals without obesity. Here, gut microbiome analysis using a biopsy-proven NAFLD cohort reveal distinct signatures of microbiome-metabolites associated with significant fibrosis in patients with NAFLD without...

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Autores principales: Giljae Lee, Hyun Ju You, Jasmohan S. Bajaj, Sae Kyung Joo, Junsun Yu, Seoyeon Park, Hyena Kang, Jeong Hwan Park, Jung Ho Kim, Dong Hyeon Lee, Seonhwa Lee, Won Kim, GwangPyo Ko
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f0a332ee4e09467eb4716ab3b8b926a7
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spelling oai:doaj.org-article:f0a332ee4e09467eb4716ab3b8b926a72021-12-02T19:16:33ZDistinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD10.1038/s41467-020-18754-52041-1723https://doaj.org/article/f0a332ee4e09467eb4716ab3b8b926a72020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18754-5https://doaj.org/toc/2041-1723Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in individuals without obesity. Here, gut microbiome analysis using a biopsy-proven NAFLD cohort reveal distinct signatures of microbiome-metabolites associated with significant fibrosis in patients with NAFLD without obesity.Giljae LeeHyun Ju YouJasmohan S. BajajSae Kyung JooJunsun YuSeoyeon ParkHyena KangJeong Hwan ParkJung Ho KimDong Hyeon LeeSeonhwa LeeWon KimGwangPyo KoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Giljae Lee
Hyun Ju You
Jasmohan S. Bajaj
Sae Kyung Joo
Junsun Yu
Seoyeon Park
Hyena Kang
Jeong Hwan Park
Jung Ho Kim
Dong Hyeon Lee
Seonhwa Lee
Won Kim
GwangPyo Ko
Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
description Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in individuals without obesity. Here, gut microbiome analysis using a biopsy-proven NAFLD cohort reveal distinct signatures of microbiome-metabolites associated with significant fibrosis in patients with NAFLD without obesity.
format article
author Giljae Lee
Hyun Ju You
Jasmohan S. Bajaj
Sae Kyung Joo
Junsun Yu
Seoyeon Park
Hyena Kang
Jeong Hwan Park
Jung Ho Kim
Dong Hyeon Lee
Seonhwa Lee
Won Kim
GwangPyo Ko
author_facet Giljae Lee
Hyun Ju You
Jasmohan S. Bajaj
Sae Kyung Joo
Junsun Yu
Seoyeon Park
Hyena Kang
Jeong Hwan Park
Jung Ho Kim
Dong Hyeon Lee
Seonhwa Lee
Won Kim
GwangPyo Ko
author_sort Giljae Lee
title Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
title_short Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
title_full Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
title_fullStr Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
title_full_unstemmed Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
title_sort distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese nafld
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f0a332ee4e09467eb4716ab3b8b926a7
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