Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases

Atherosclerosis (AS) is a systemic chronic disease affecting both the coronary and cerebral arteries. Inflammation plays a key role in the initiation and progression of AS, and numerous inflammatory factors have been proposed as potential biomarkers. This article reviews recent research in studies o...

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Autores principales: Jun-Xuan Lv, Qi Kong, Xin Ma
Formato: article
Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2017
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Acceso en línea:https://doaj.org/article/f0a36112a3344ffe82d688ae6d17c9a4
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spelling oai:doaj.org-article:f0a36112a3344ffe82d688ae6d17c9a42021-12-02T13:28:50ZCurrent advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases2095-882X10.1016/j.cdtm.2017.09.002https://doaj.org/article/f0a36112a3344ffe82d688ae6d17c9a42017-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X17300713https://doaj.org/toc/2095-882XAtherosclerosis (AS) is a systemic chronic disease affecting both the coronary and cerebral arteries. Inflammation plays a key role in the initiation and progression of AS, and numerous inflammatory factors have been proposed as potential biomarkers. This article reviews recent research in studies on major circulating inflammatory biomarkers to identify surrogates that may reflect processes associated with AS development and the risk of AS-related vascular events, such as Von Willebrand factor, lectin-like oxidized low-density-lipoprotein receptor-1, soluble urokinase plasminogen activator receptor, regulated upon activation, normal T-cell expressed and secreted, and microparticles, which may provide new perspectives for clinical AS evaluation and risk stratification.Jun-Xuan LvQi KongXin MaKeAi Communications Co., Ltd.articleAtherosclerosisPlaquesInflammatory biomarkersRisk factorsMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 3, Iss 4, Pp 207-212 (2017)
institution DOAJ
collection DOAJ
language EN
topic Atherosclerosis
Plaques
Inflammatory biomarkers
Risk factors
Medicine (General)
R5-920
spellingShingle Atherosclerosis
Plaques
Inflammatory biomarkers
Risk factors
Medicine (General)
R5-920
Jun-Xuan Lv
Qi Kong
Xin Ma
Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
description Atherosclerosis (AS) is a systemic chronic disease affecting both the coronary and cerebral arteries. Inflammation plays a key role in the initiation and progression of AS, and numerous inflammatory factors have been proposed as potential biomarkers. This article reviews recent research in studies on major circulating inflammatory biomarkers to identify surrogates that may reflect processes associated with AS development and the risk of AS-related vascular events, such as Von Willebrand factor, lectin-like oxidized low-density-lipoprotein receptor-1, soluble urokinase plasminogen activator receptor, regulated upon activation, normal T-cell expressed and secreted, and microparticles, which may provide new perspectives for clinical AS evaluation and risk stratification.
format article
author Jun-Xuan Lv
Qi Kong
Xin Ma
author_facet Jun-Xuan Lv
Qi Kong
Xin Ma
author_sort Jun-Xuan Lv
title Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
title_short Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
title_full Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
title_fullStr Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
title_full_unstemmed Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
title_sort current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
publisher KeAi Communications Co., Ltd.
publishDate 2017
url https://doaj.org/article/f0a36112a3344ffe82d688ae6d17c9a4
work_keys_str_mv AT junxuanlv currentadvancesincirculatinginflammatorybiomarkersinatherosclerosisandrelatedcardiocerebrovasculardiseases
AT qikong currentadvancesincirculatinginflammatorybiomarkersinatherosclerosisandrelatedcardiocerebrovasculardiseases
AT xinma currentadvancesincirculatinginflammatorybiomarkersinatherosclerosisandrelatedcardiocerebrovasculardiseases
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