Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)

Abstract To assess the surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK) for recurrent disease after initial PTK. Retrospective cohort study with historical comparison group. This study involved 56 patients who underwent re-PTK (mean follow-up period: 47.9 ± 36.2 months) at...

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Autores principales:	Osamu Hieda, Chie Sotozono, Yo Nakamura, Koichi Wakimasu, Shigeru Kinoshita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f0a3c7651c8d4766a6161d3ca784e849
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spelling	oai:doaj.org-article:f0a3c7651c8d4766a6161d3ca784e8492021-12-02T17:51:21ZSurgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)10.1038/s41598-021-91121-62045-2322https://doaj.org/article/f0a3c7651c8d4766a6161d3ca784e8492021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91121-6https://doaj.org/toc/2045-2322Abstract To assess the surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK) for recurrent disease after initial PTK. Retrospective cohort study with historical comparison group. This study involved 56 patients who underwent re-PTK (mean follow-up period: 47.9 ± 36.2 months) at the Baptist Eye Institute, Kyoto, Japan. In all subjects, corrected-distance visual acuity (CDVA) before and after re-PTK was compared. Postoperative recurrence of corneal lesion with a decrease of CDVA of two lines or more was compared with postoperative best CDVA deemed as a significant relapse. The Kaplan–Meier method was used to compare the recurrence rate post-re-PTK with that after the initial PTK. The disease classification in the 78 eyes was heterozygous-type GCD (hetero-GCD, n = 47 eyes), homozygous-type GCD (homo-GCD, n = 13 eyes), band keratopathy (n = 7 eyes), lattice corneal dystrophy (n = 6 eyes), and other (n = 5 eyes). After re-PTK, homo-GCD recurred statistically significantly earlier than hetero-GCD (P = 0.0042). No significant difference was found in the recurrence rate for all diseases between post-re-PTK and post initial PTK (P > 0.05). Surgical outcomes after re-PTK were nearly equal to those after initial-PTK.Osamu HiedaChie SotozonoYo NakamuraKoichi WakimasuShigeru KinoshitaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Osamu Hieda Chie Sotozono Yo Nakamura Koichi Wakimasu Shigeru Kinoshita Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)
description	Abstract To assess the surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK) for recurrent disease after initial PTK. Retrospective cohort study with historical comparison group. This study involved 56 patients who underwent re-PTK (mean follow-up period: 47.9 ± 36.2 months) at the Baptist Eye Institute, Kyoto, Japan. In all subjects, corrected-distance visual acuity (CDVA) before and after re-PTK was compared. Postoperative recurrence of corneal lesion with a decrease of CDVA of two lines or more was compared with postoperative best CDVA deemed as a significant relapse. The Kaplan–Meier method was used to compare the recurrence rate post-re-PTK with that after the initial PTK. The disease classification in the 78 eyes was heterozygous-type GCD (hetero-GCD, n = 47 eyes), homozygous-type GCD (homo-GCD, n = 13 eyes), band keratopathy (n = 7 eyes), lattice corneal dystrophy (n = 6 eyes), and other (n = 5 eyes). After re-PTK, homo-GCD recurred statistically significantly earlier than hetero-GCD (P = 0.0042). No significant difference was found in the recurrence rate for all diseases between post-re-PTK and post initial PTK (P > 0.05). Surgical outcomes after re-PTK were nearly equal to those after initial-PTK.
format	article
author	Osamu Hieda Chie Sotozono Yo Nakamura Koichi Wakimasu Shigeru Kinoshita
author_facet	Osamu Hieda Chie Sotozono Yo Nakamura Koichi Wakimasu Shigeru Kinoshita
author_sort	Osamu Hieda
title	Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)
title_short	Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)
title_full	Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)
title_fullStr	Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)
title_full_unstemmed	Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)
title_sort	surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-ptk)
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f0a3c7651c8d4766a6161d3ca784e849
work_keys_str_mv	AT osamuhieda surgicaloutcomesofreexcimerlaserphototherapeutickeratectomyreptk AT chiesotozono surgicaloutcomesofreexcimerlaserphototherapeutickeratectomyreptk AT yonakamura surgicaloutcomesofreexcimerlaserphototherapeutickeratectomyreptk AT koichiwakimasu surgicaloutcomesofreexcimerlaserphototherapeutickeratectomyreptk AT shigerukinoshita surgicaloutcomesofreexcimerlaserphototherapeutickeratectomyreptk
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Surgical outcomes of re-excimer laser phototherapeutic keratectomy (re-PTK)

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