Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.
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Nature Portfolio
2016
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oai:doaj.org-article:f0a67b918c38454580d5502fe31af9b82021-12-02T14:39:14ZDendritic excitation–inhibition balance shapes cerebellar output during motor behaviour10.1038/ncomms137222041-1723https://doaj.org/article/f0a67b918c38454580d5502fe31af9b82016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13722https://doaj.org/toc/2041-1723Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.Marta JelitaiPaolo PuggioniTaro IshikawaArianna RinaldiIan DuguidNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q Marta Jelitai Paolo Puggioni Taro Ishikawa Arianna Rinaldi Ian Duguid Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour |
description |
Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour. |
format |
article |
author |
Marta Jelitai Paolo Puggioni Taro Ishikawa Arianna Rinaldi Ian Duguid |
author_facet |
Marta Jelitai Paolo Puggioni Taro Ishikawa Arianna Rinaldi Ian Duguid |
author_sort |
Marta Jelitai |
title |
Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour |
title_short |
Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour |
title_full |
Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour |
title_fullStr |
Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour |
title_full_unstemmed |
Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour |
title_sort |
dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/f0a67b918c38454580d5502fe31af9b8 |
work_keys_str_mv |
AT martajelitai dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT paolopuggioni dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT taroishikawa dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT ariannarinaldi dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT ianduguid dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour |
_version_ |
1718390747598684160 |