Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour

Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.

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Autores principales: Marta Jelitai, Paolo Puggioni, Taro Ishikawa, Arianna Rinaldi, Ian Duguid
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/f0a67b918c38454580d5502fe31af9b8
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spelling oai:doaj.org-article:f0a67b918c38454580d5502fe31af9b82021-12-02T14:39:14ZDendritic excitation–inhibition balance shapes cerebellar output during motor behaviour10.1038/ncomms137222041-1723https://doaj.org/article/f0a67b918c38454580d5502fe31af9b82016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13722https://doaj.org/toc/2041-1723Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.Marta JelitaiPaolo PuggioniTaro IshikawaArianna RinaldiIan DuguidNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marta Jelitai
Paolo Puggioni
Taro Ishikawa
Arianna Rinaldi
Ian Duguid
Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
description Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.
format article
author Marta Jelitai
Paolo Puggioni
Taro Ishikawa
Arianna Rinaldi
Ian Duguid
author_facet Marta Jelitai
Paolo Puggioni
Taro Ishikawa
Arianna Rinaldi
Ian Duguid
author_sort Marta Jelitai
title Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_short Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_full Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_fullStr Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_full_unstemmed Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_sort dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/f0a67b918c38454580d5502fe31af9b8
work_keys_str_mv AT martajelitai dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour
AT paolopuggioni dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour
AT taroishikawa dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour
AT ariannarinaldi dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour
AT ianduguid dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour
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