Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour

Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.

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Autores principales:	Marta Jelitai, Paolo Puggioni, Taro Ishikawa, Arianna Rinaldi, Ian Duguid
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f0a67b918c38454580d5502fe31af9b8
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spelling	oai:doaj.org-article:f0a67b918c38454580d5502fe31af9b82021-12-02T14:39:14ZDendritic excitation–inhibition balance shapes cerebellar output during motor behaviour10.1038/ncomms137222041-1723https://doaj.org/article/f0a67b918c38454580d5502fe31af9b82016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13722https://doaj.org/toc/2041-1723Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.Marta JelitaiPaolo PuggioniTaro IshikawaArianna RinaldiIan DuguidNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marta Jelitai Paolo Puggioni Taro Ishikawa Arianna Rinaldi Ian Duguid Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
description	Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.
format	article
author	Marta Jelitai Paolo Puggioni Taro Ishikawa Arianna Rinaldi Ian Duguid
author_facet	Marta Jelitai Paolo Puggioni Taro Ishikawa Arianna Rinaldi Ian Duguid
author_sort	Marta Jelitai
title	Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_short	Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_full	Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_fullStr	Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_full_unstemmed	Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
title_sort	dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f0a67b918c38454580d5502fe31af9b8
work_keys_str_mv	AT martajelitai dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT paolopuggioni dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT taroishikawa dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT ariannarinaldi dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour AT ianduguid dendriticexcitationinhibitionbalanceshapescerebellaroutputduringmotorbehaviour
_version_	1718390747598684160

Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour

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