Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages

AIM: To assess and compare the effectiveness of selective laser trabeculoplasty(SLT)in preventing primary open angle glaucoma(POAG)with various stages.METHODS: Fifty-one eyes of 27 patients 51 eye with POAG were included in this retrospective study. All the cases were divided into three groups depen...

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Autores principales:	Yu Zhou, Ming-Xing Wu, Lan-Jiao Li
Formato:	article
Lenguaje:	EN
Publicado:	Press of International Journal of Ophthalmology (IJO PRESS) 2021
Materias:	selective laser trabeculoplasty primary open angle glaucoma intraocular pressure Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f0a84d5eaf92457cac5bd4613824962a
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spelling	oai:doaj.org-article:f0a84d5eaf92457cac5bd4613824962a2021-11-22T14:22:33ZEffect of selective laser trabeculoplasty on primary open angle glaucoma in different stages1672-512310.3980/j.issn.1672-5123.2021.12.18https://doaj.org/article/f0a84d5eaf92457cac5bd4613824962a2021-12-01T00:00:00Zhttp://ies.ijo.cn/cn_publish/2021/12/202112018.pdfhttps://doaj.org/toc/1672-5123AIM: To assess and compare the effectiveness of selective laser trabeculoplasty(SLT)in preventing primary open angle glaucoma(POAG)with various stages.METHODS: Fifty-one eyes of 27 patients 51 eye with POAG were included in this retrospective study. All the cases were divided into three groups depending on the mean deviation(MD): the early stage group(MD>-6dB, 15 eyes), middle stage group(-12dB≤MD≤-6dB, 15 eyes)and late stage group(MD<-12dB, 21 eyes). All subjects underwent SLT on 360° of the angle between July 2018 to March 2020. The laser parameters of a 532nm, Q-switched, frequency-doubled Nd: YAG laser, with 3ns pulse time, 400μm spot diameter were set to selectively target pigmented trabecular meshwork cells without visible damage to the adjacent non-pigmented tissue. Intraocular pressure(IOP)reduction was observed at 1h, 1d, 1, 3, 6 and 12mo after the laser procedure. Meanwhile, the ratio of the IOP reduction, visual field index(VFI), MD, medication, adverse reactions and efficiency were assessed as well.RESULTS: Within the 12mo post-SLT, there were no statistically significant differences for the IOP and IOP decline rate between each group(all P>0.05). There were significant differences in VFI and MD among early, middle and late groups(P<0.001), within the 12mo post-SLT, no statistically significant differences were detected for the decline of VFI and MD in each group. In terms of the early stage group, the effective rates of SLT at 1, 3, 6 and 12mo after treatment were 100%, 93%, 87%, 67%, respectively. For the middle stage group and late stage group, the effective rates were 87%, 80%, 93%, 60%, and 67%, 71%, 62%, 19%, respectively. CONCLUSION: SLT was an effective treatment for POAG patients in various stages, while the effective rate decreased with time.Yu ZhouMing-Xing WuLan-Jiao LiPress of International Journal of Ophthalmology (IJO PRESS)articleselective laser trabeculoplastyprimary open angle glaucomaintraocular pressureOphthalmologyRE1-994ENGuoji Yanke Zazhi, Vol 21, Iss 12, Pp 2113-2117 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	selective laser trabeculoplasty primary open angle glaucoma intraocular pressure Ophthalmology RE1-994
spellingShingle	selective laser trabeculoplasty primary open angle glaucoma intraocular pressure Ophthalmology RE1-994 Yu Zhou Ming-Xing Wu Lan-Jiao Li Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages
description	AIM: To assess and compare the effectiveness of selective laser trabeculoplasty(SLT)in preventing primary open angle glaucoma(POAG)with various stages.METHODS: Fifty-one eyes of 27 patients 51 eye with POAG were included in this retrospective study. All the cases were divided into three groups depending on the mean deviation(MD): the early stage group(MD>-6dB, 15 eyes), middle stage group(-12dB≤MD≤-6dB, 15 eyes)and late stage group(MD<-12dB, 21 eyes). All subjects underwent SLT on 360° of the angle between July 2018 to March 2020. The laser parameters of a 532nm, Q-switched, frequency-doubled Nd: YAG laser, with 3ns pulse time, 400μm spot diameter were set to selectively target pigmented trabecular meshwork cells without visible damage to the adjacent non-pigmented tissue. Intraocular pressure(IOP)reduction was observed at 1h, 1d, 1, 3, 6 and 12mo after the laser procedure. Meanwhile, the ratio of the IOP reduction, visual field index(VFI), MD, medication, adverse reactions and efficiency were assessed as well.RESULTS: Within the 12mo post-SLT, there were no statistically significant differences for the IOP and IOP decline rate between each group(all P>0.05). There were significant differences in VFI and MD among early, middle and late groups(P<0.001), within the 12mo post-SLT, no statistically significant differences were detected for the decline of VFI and MD in each group. In terms of the early stage group, the effective rates of SLT at 1, 3, 6 and 12mo after treatment were 100%, 93%, 87%, 67%, respectively. For the middle stage group and late stage group, the effective rates were 87%, 80%, 93%, 60%, and 67%, 71%, 62%, 19%, respectively. CONCLUSION: SLT was an effective treatment for POAG patients in various stages, while the effective rate decreased with time.
format	article
author	Yu Zhou Ming-Xing Wu Lan-Jiao Li
author_facet	Yu Zhou Ming-Xing Wu Lan-Jiao Li
author_sort	Yu Zhou
title	Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages
title_short	Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages
title_full	Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages
title_fullStr	Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages
title_full_unstemmed	Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages
title_sort	effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages
publisher	Press of International Journal of Ophthalmology (IJO PRESS)
publishDate	2021
url	https://doaj.org/article/f0a84d5eaf92457cac5bd4613824962a
work_keys_str_mv	AT yuzhou effectofselectivelasertrabeculoplastyonprimaryopenangleglaucomaindifferentstages AT mingxingwu effectofselectivelasertrabeculoplastyonprimaryopenangleglaucomaindifferentstages AT lanjiaoli effectofselectivelasertrabeculoplastyonprimaryopenangleglaucomaindifferentstages
_version_	1718417590051667968

Effect of selective laser trabeculoplasty on primary open angle glaucoma in different stages

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