Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation

Background: Midline cerebral structures are essential for the normal morphogenesis and function of the fetal brain. However, the diagnosis of congenital anomalies of midline cerebral structures. The Aim of The Work: This study aimed to evaluate the role of 2D versus 4D ultrasound in the diagnosis of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ahmed Bedeir Abd El Salam, Faisal Mustafa, Zainab Sayed, Hamada Abuelmatti
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Materias:	two-dimensional four-dimensional fetal brain midline structures postnatal transcranial ultrasound Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f0acc66b2f2b48e982f6be64d076dfe1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f0acc66b2f2b48e982f6be64d076dfe1
record_format	dspace
spelling	oai:doaj.org-article:f0acc66b2f2b48e982f6be64d076dfe12021-12-02T18:11:42ZUltrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation2636-41742682-378010.21608/ijma.2021.200543https://doaj.org/article/f0acc66b2f2b48e982f6be64d076dfe12021-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_200543_58d9a1be8c555c52ecec410c1eccc684.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Midline cerebral structures are essential for the normal morphogenesis and function of the fetal brain. However, the diagnosis of congenital anomalies of midline cerebral structures. The Aim of The Work: This study aimed to evaluate the role of 2D versus 4D ultrasound in the diagnosis of midline structures of the fetal brain at the second trimester of pregnancy.Patients and Methods: 200 pregnant women at the second trimester [18-22 weeks] were selected. They were clinically evaluated to check the female and fetal wellbeing. Then a screening of fetal brain midline strictures had been performed by two- and four-dimensional ultrasound, aiming to discover any anomalies of the fetal brain midline structure. Both scans were compared with the postnatal transcranial ultrasound.Results: The 2D ultrasound detected no abnormality in 194 out of 200 fetuses [97.0%], and 4 cases [2.0%] had mega-cisterna magna, and 2 cases [1.0%] had encephalomylocele, which were detected by the 4 D and confirmed by postnatal transcranial ultrasound. The 4 D US discovered 2 cases [1.0%] of Dandywalker malformation, which was confirmed by postnatal transcranial US. There was a complete agreement between prenatal 4D ultrasound and postnatal transcranial ultrasound. The prenatal 2D ultrasound had a sensitivity of 75.0%, specificity of 100.0%, PPV of 100.0%, NPV of 98.7% and overall accuracy of 99.0%. Otherwise, the prenatal 4D ultrasound was 100.0% sensitive and specific. Conclusion: 4D ultrasound showed superiority in the diagnosis and confirmation of the fetal brain midline structure’s abnormalities. Also, the prenatal 4D ultrasound was 100.0% sensitive as postnatal transcranial US.Ahmed Bedeir Abd El SalamFaisal MustafaZainab SayedHamada AbuelmattiAl-Azhar University, Faculty of Medicine (Damietta)articletwo-dimensionalfour-dimensionalfetal brain midline structurespostnataltranscranial ultrasoundMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 4, Pp 1811-1817 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	two-dimensional four-dimensional fetal brain midline structures postnatal transcranial ultrasound Medicine (General) R5-920
spellingShingle	two-dimensional four-dimensional fetal brain midline structures postnatal transcranial ultrasound Medicine (General) R5-920 Ahmed Bedeir Abd El Salam Faisal Mustafa Zainab Sayed Hamada Abuelmatti Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation
description	Background: Midline cerebral structures are essential for the normal morphogenesis and function of the fetal brain. However, the diagnosis of congenital anomalies of midline cerebral structures. The Aim of The Work: This study aimed to evaluate the role of 2D versus 4D ultrasound in the diagnosis of midline structures of the fetal brain at the second trimester of pregnancy.Patients and Methods: 200 pregnant women at the second trimester [18-22 weeks] were selected. They were clinically evaluated to check the female and fetal wellbeing. Then a screening of fetal brain midline strictures had been performed by two- and four-dimensional ultrasound, aiming to discover any anomalies of the fetal brain midline structure. Both scans were compared with the postnatal transcranial ultrasound.Results: The 2D ultrasound detected no abnormality in 194 out of 200 fetuses [97.0%], and 4 cases [2.0%] had mega-cisterna magna, and 2 cases [1.0%] had encephalomylocele, which were detected by the 4 D and confirmed by postnatal transcranial ultrasound. The 4 D US discovered 2 cases [1.0%] of Dandywalker malformation, which was confirmed by postnatal transcranial US. There was a complete agreement between prenatal 4D ultrasound and postnatal transcranial ultrasound. The prenatal 2D ultrasound had a sensitivity of 75.0%, specificity of 100.0%, PPV of 100.0%, NPV of 98.7% and overall accuracy of 99.0%. Otherwise, the prenatal 4D ultrasound was 100.0% sensitive and specific. Conclusion: 4D ultrasound showed superiority in the diagnosis and confirmation of the fetal brain midline structure’s abnormalities. Also, the prenatal 4D ultrasound was 100.0% sensitive as postnatal transcranial US.
format	article
author	Ahmed Bedeir Abd El Salam Faisal Mustafa Zainab Sayed Hamada Abuelmatti
author_facet	Ahmed Bedeir Abd El Salam Faisal Mustafa Zainab Sayed Hamada Abuelmatti
author_sort	Ahmed Bedeir Abd El Salam
title	Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation
title_short	Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation
title_full	Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation
title_fullStr	Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation
title_full_unstemmed	Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation
title_sort	ultrasonographic evaluation of fetal brain midline structures in the second trimester: the role of 2d versus 4d, with post-natal correlation
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/f0acc66b2f2b48e982f6be64d076dfe1
work_keys_str_mv	AT ahmedbedeirabdelsalam ultrasonographicevaluationoffetalbrainmidlinestructuresinthesecondtrimestertheroleof2dversus4dwithpostnatalcorrelation AT faisalmustafa ultrasonographicevaluationoffetalbrainmidlinestructuresinthesecondtrimestertheroleof2dversus4dwithpostnatalcorrelation AT zainabsayed ultrasonographicevaluationoffetalbrainmidlinestructuresinthesecondtrimestertheroleof2dversus4dwithpostnatalcorrelation AT hamadaabuelmatti ultrasonographicevaluationoffetalbrainmidlinestructuresinthesecondtrimestertheroleof2dversus4dwithpostnatalcorrelation
_version_	1718378608120037376

Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation

Ejemplares similares