Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

Abstract The highly conserved Wnt signaling pathway regulates cell proliferation and differentiation in vertebrates and invertebrates. Upon binding of a Wnt ligand to a receptor of the Fz family, Disheveled (Dsh/Dvl) transduces the signal during canonical and non-canonical Wnt signaling. The specifi...

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Autores principales: Prameet Kaur, Vanessa Yuk Man Lam, Anirudh Gautam Mannava, Jahnavi Suresh, Andreas Jenny, Nicholas S. Tolwinski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/f0b54aded1a04e80b4c93f85536b5bf0
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