A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia

The molecular pathway(s) driving antipsychotics (AP) induced hyperphagia remains unclear. A novel C. elegans system is used here to screen for FDA approved drugs that selectively suppresses this response, unraveling potential molecular mediators influencing AP induced hyperphagia in mouse models.

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Bibliographic Details
Main Authors: Anabel Perez-Gomez, Maria Carretero, Natalie Weber, Veronika Peterka, Alan To, Viktoriya Titova, Gregory Solis, Olivia Osborn, Michael Petrascheck
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
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Online Access:https://doaj.org/article/f0bb27eb5a4746e6b17de6526ad7e3a7
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