Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab
Introduction: The male genital system consists of the prostate, seminal vesicle, testes, epididymis, vas deferens, bulbourethral gland, ejaculatory duct, penis and scrotum. Male genital cancers are histologically diverse. They are difficult to detect and treat because of their anatomic locations...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
JCDR Research and Publications Private Limited
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/f0c895c8221241958b3828b07809caa7 |
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| Sumario: | Introduction: The male genital system consists of the prostate,
seminal vesicle, testes, epididymis, vas deferens, bulbourethral
gland, ejaculatory duct, penis and scrotum. Male genital cancers
are histologically diverse. They are difficult to detect and treat
because of their anatomic locations, biological characters and
complications.
Aim: To study the histopathological spectrum of tumours of the
male genital system according to World Health Organisation (WHO)
classification.
Materials and Methods: The present study is a hospital based
descriptive study conducted in the Department of Pathology,
Guru Gobind Singh Medical College and Hospital, Faridkot,
Punjab, India, during February 2019 to August 2020 which
included 128 cases. All biopsies, specimens and review blocks
and slides of male genital tract tumours were processed and
slides were stained with Haematoxylin and Eosin (H&E) stain.
Serum tumour markers and immunohistochemical stains were
used. The clinical information including symptoms related to the
male genital system, histopathological findings and diagnosis
were recorded on the predesigned proforma. Other necessary
information was collected from the requisition form received
along with the biopsy material. The association between categorical
variables was explored using Pearson’s Chi-square test. A p-value
<0.05 was considered statistically significant for this study.
Results: The present study included 128 cases, of which the majority
of the cases 82 cases (64%) were that of prostate, 28 cases (21.9%)
of the penis, 15 cases (11.7%) of testes, two cases (1.6%) were
that of the scrotum and one case (0.8%) was of the epididymis.
The histopathological spectrum showed adenocarcinoma was
present in 80 (62.5%), leiomyosarcoma in 01 (0.8%), lymphoma in
01 (0.8%), mixed germ cell tumour in 9 (7%), seminoma in 5 (3.9%),
postpubertal teratoma in 1 (0.8%), basaloid in 1 (0.8%), papillarybasaloid in 2 (1.6%).
Conclusion: Prostate tumours outnumbered all other tumours of
the male genital tract with adenocarcinoma of prostate followed
by squamous cell carcinoma of the penis and mixed Germ Cell
Tumour (GCT) of testes. The present study provides updated
information regarding the histopathological spectrum of male
genital system tumours. |
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