Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.

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Autores principales: María-Victoria Hinckelmann, Amandine Virlogeux, Christian Niehage, Christel Poujol, Daniel Choquet, Bernard Hoflack, Diana Zala, Frédéric Saudou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd6
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spelling oai:doaj.org-article:f0cf3b40a24c4fd88c6947f5f247fbd62021-12-02T14:38:56ZSelf-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport10.1038/ncomms132332041-1723https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd62016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13233https://doaj.org/toc/2041-1723How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.María-Victoria HinckelmannAmandine VirlogeuxChristian NiehageChristel PoujolDaniel ChoquetBernard HoflackDiana ZalaFrédéric SaudouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
María-Victoria Hinckelmann
Amandine Virlogeux
Christian Niehage
Christel Poujol
Daniel Choquet
Bernard Hoflack
Diana Zala
Frédéric Saudou
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
description How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.
format article
author María-Victoria Hinckelmann
Amandine Virlogeux
Christian Niehage
Christel Poujol
Daniel Choquet
Bernard Hoflack
Diana Zala
Frédéric Saudou
author_facet María-Victoria Hinckelmann
Amandine Virlogeux
Christian Niehage
Christel Poujol
Daniel Choquet
Bernard Hoflack
Diana Zala
Frédéric Saudou
author_sort María-Victoria Hinckelmann
title Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_short Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_full Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_fullStr Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_full_unstemmed Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_sort self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd6
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