Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.

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Main Authors:	María-Victoria Hinckelmann, Amandine Virlogeux, Christian Niehage, Christel Poujol, Daniel Choquet, Bernard Hoflack, Diana Zala, Frédéric Saudou
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd6
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spelling	oai:doaj.org-article:f0cf3b40a24c4fd88c6947f5f247fbd62021-12-02T14:38:56ZSelf-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport10.1038/ncomms132332041-1723https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd62016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13233https://doaj.org/toc/2041-1723How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.María-Victoria HinckelmannAmandine VirlogeuxChristian NiehageChristel PoujolDaniel ChoquetBernard HoflackDiana ZalaFrédéric SaudouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q María-Victoria Hinckelmann Amandine Virlogeux Christian Niehage Christel Poujol Daniel Choquet Bernard Hoflack Diana Zala Frédéric Saudou Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
description	How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.
format	article
author	María-Victoria Hinckelmann Amandine Virlogeux Christian Niehage Christel Poujol Daniel Choquet Bernard Hoflack Diana Zala Frédéric Saudou
author_facet	María-Victoria Hinckelmann Amandine Virlogeux Christian Niehage Christel Poujol Daniel Choquet Bernard Hoflack Diana Zala Frédéric Saudou
author_sort	María-Victoria Hinckelmann
title	Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_short	Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_full	Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_fullStr	Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_full_unstemmed	Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
title_sort	self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd6
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Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

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