Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.
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2016
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oai:doaj.org-article:f0cf3b40a24c4fd88c6947f5f247fbd62021-12-02T14:38:56ZSelf-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport10.1038/ncomms132332041-1723https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd62016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13233https://doaj.org/toc/2041-1723How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.María-Victoria HinckelmannAmandine VirlogeuxChristian NiehageChristel PoujolDaniel ChoquetBernard HoflackDiana ZalaFrédéric SaudouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q María-Victoria Hinckelmann Amandine Virlogeux Christian Niehage Christel Poujol Daniel Choquet Bernard Hoflack Diana Zala Frédéric Saudou Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport |
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How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay. |
format |
article |
author |
María-Victoria Hinckelmann Amandine Virlogeux Christian Niehage Christel Poujol Daniel Choquet Bernard Hoflack Diana Zala Frédéric Saudou |
author_facet |
María-Victoria Hinckelmann Amandine Virlogeux Christian Niehage Christel Poujol Daniel Choquet Bernard Hoflack Diana Zala Frédéric Saudou |
author_sort |
María-Victoria Hinckelmann |
title |
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport |
title_short |
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport |
title_full |
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport |
title_fullStr |
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport |
title_full_unstemmed |
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport |
title_sort |
self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/f0cf3b40a24c4fd88c6947f5f247fbd6 |
work_keys_str_mv |
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