Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction
SARS-CoV-2 viral attachment and entry into host cells is mediated by a direct interaction between viral spike glycoproteins and membrane bound angiotensin-converting enzyme 2 (ACE2). The receptor binding motif (RBM), located within the S1 subunit of the spike protein, incorporates the majority of kn...
Guardado en:
Autores principales: | Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C. Morgan, Wendy Beattie, Augusto C. Montezano, Brian Hudson, Andrew B. Tobin, David Bhella, Rhian M. Touyz, Andrew G. Jamieson, George S. Baillie, Connor M. Blair |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f0f07f9a6ed44895934fa969a58c9b5e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction.
por: Amit Mahindra, et al.
Publicado: (2021) -
Polyunsaturated ω-3 fatty acids inhibit ACE2-controlled SARS-CoV-2 binding and cellular entry
por: Anna Goc, et al.
Publicado: (2021) -
The molecular basis for SARS-CoV-2 binding to dog ACE2
por: Zengyuan Zhang, et al.
Publicado: (2021) -
SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity
por: Seiya Ozono, et al.
Publicado: (2021) -
Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
por: Jinsung Yang, et al.
Publicado: (2020)