Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction
SARS-CoV-2 viral attachment and entry into host cells is mediated by a direct interaction between viral spike glycoproteins and membrane bound angiotensin-converting enzyme 2 (ACE2). The receptor binding motif (RBM), located within the S1 subunit of the spike protein, incorporates the majority of kn...
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2021
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| Accès en ligne: | https://doaj.org/article/f0f07f9a6ed44895934fa969a58c9b5e |
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par Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C Morgan, Wendy Beattie, Augusto C Montezano, Brian Hudson, Andrew B Tobin, David Bhella, Rhian M Touyz, Andrew G Jamieson, George S Baillie, Connor M Blair
Publié 2021
Accéder au texte intégralPublié 2021
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