Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort

Abstract The association of visual impairment and depression has been investigated in several studies based on a cross-sectional design, which cannot delineate temporal relationships. In the present study, we evaluated the influence of visual impairment on depression in all age groups using a longit...

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Autores principales:	Hyo Geun Choi, Min Joung Lee, Sang-Mok Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f0f4a46679bf4cff83bde88249e3cfed
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spelling	oai:doaj.org-article:f0f4a46679bf4cff83bde88249e3cfed2021-12-02T15:08:35ZVisual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort10.1038/s41598-018-20374-52045-2322https://doaj.org/article/f0f4a46679bf4cff83bde88249e3cfed2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-20374-5https://doaj.org/toc/2045-2322Abstract The association of visual impairment and depression has been investigated in several studies based on a cross-sectional design, which cannot delineate temporal relationships. In the present study, we evaluated the influence of visual impairment on depression in all age groups using a longitudinal database of a national sample cohort from 2002 to 2013 provided by the Korean National Health Insurance Service. Of a total of 1,025,340 subjects, 5,846 participants who were registered as visually impaired persons without a previous diagnosis of depression were enrolled at a 1:4 ratio with 23,384 control participants matched for age, sex, income, and region of residence. The crude and adjusted (age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia) hazard ratios (HRs) for the development of depression between the visually impaired and control groups were analyzed using a Cox proportional hazards model. Visual impairment increased the risk of depression after adjusting for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia (adjusted HR = 1.19, P = 0.002). The risk of depression increased significantly in both the non-blindness visual impairment (adjusted HR = 1.15, P = 0.036) and blindness subgroups (adjusted HR = 1.31, P = 0.016), with a higher HR in the blindness subgroup.Hyo Geun ChoiMin Joung LeeSang-Mok LeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hyo Geun Choi Min Joung Lee Sang-Mok Lee Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort
description	Abstract The association of visual impairment and depression has been investigated in several studies based on a cross-sectional design, which cannot delineate temporal relationships. In the present study, we evaluated the influence of visual impairment on depression in all age groups using a longitudinal database of a national sample cohort from 2002 to 2013 provided by the Korean National Health Insurance Service. Of a total of 1,025,340 subjects, 5,846 participants who were registered as visually impaired persons without a previous diagnosis of depression were enrolled at a 1:4 ratio with 23,384 control participants matched for age, sex, income, and region of residence. The crude and adjusted (age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia) hazard ratios (HRs) for the development of depression between the visually impaired and control groups were analyzed using a Cox proportional hazards model. Visual impairment increased the risk of depression after adjusting for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia (adjusted HR = 1.19, P = 0.002). The risk of depression increased significantly in both the non-blindness visual impairment (adjusted HR = 1.15, P = 0.036) and blindness subgroups (adjusted HR = 1.31, P = 0.016), with a higher HR in the blindness subgroup.
format	article
author	Hyo Geun Choi Min Joung Lee Sang-Mok Lee
author_facet	Hyo Geun Choi Min Joung Lee Sang-Mok Lee
author_sort	Hyo Geun Choi
title	Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort
title_short	Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort
title_full	Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort
title_fullStr	Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort
title_full_unstemmed	Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort
title_sort	visual impairment and risk of depression: a longitudinal follow-up study using a national sample cohort
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f0f4a46679bf4cff83bde88249e3cfed
work_keys_str_mv	AT hyogeunchoi visualimpairmentandriskofdepressionalongitudinalfollowupstudyusinganationalsamplecohort AT minjounglee visualimpairmentandriskofdepressionalongitudinalfollowupstudyusinganationalsamplecohort AT sangmoklee visualimpairmentandriskofdepressionalongitudinalfollowupstudyusinganationalsamplecohort
_version_	1718388098521366528

Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort

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