Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif

The Y complex is an essential component of the nuclear pore complex but a full model based on experimental structures is lacking. Here, the authors complete the model of the yeast Y complex with two nanobody-bound crystal structures, providing molecular insights into its flexibility and membrane anc...

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Autores principales: Sarah A. Nordeen, Daniel L. Turman, Thomas U. Schwartz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f0fe30db2f3249699674892162af134e
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spelling oai:doaj.org-article:f0fe30db2f3249699674892162af134e2021-12-02T14:40:52ZYeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif10.1038/s41467-020-19885-52041-1723https://doaj.org/article/f0fe30db2f3249699674892162af134e2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19885-5https://doaj.org/toc/2041-1723The Y complex is an essential component of the nuclear pore complex but a full model based on experimental structures is lacking. Here, the authors complete the model of the yeast Y complex with two nanobody-bound crystal structures, providing molecular insights into its flexibility and membrane anchoring.Sarah A. NordeenDaniel L. TurmanThomas U. SchwartzNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sarah A. Nordeen
Daniel L. Turman
Thomas U. Schwartz
Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
description The Y complex is an essential component of the nuclear pore complex but a full model based on experimental structures is lacking. Here, the authors complete the model of the yeast Y complex with two nanobody-bound crystal structures, providing molecular insights into its flexibility and membrane anchoring.
format article
author Sarah A. Nordeen
Daniel L. Turman
Thomas U. Schwartz
author_facet Sarah A. Nordeen
Daniel L. Turman
Thomas U. Schwartz
author_sort Sarah A. Nordeen
title Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
title_short Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
title_full Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
title_fullStr Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
title_full_unstemmed Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
title_sort yeast nup84-nup133 complex structure details flexibility and reveals conservation of the membrane anchoring alps motif
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f0fe30db2f3249699674892162af134e
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AT daniellturman yeastnup84nup133complexstructuredetailsflexibilityandrevealsconservationofthemembraneanchoringalpsmotif
AT thomasuschwartz yeastnup84nup133complexstructuredetailsflexibilityandrevealsconservationofthemembraneanchoringalpsmotif
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