Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
The Y complex is an essential component of the nuclear pore complex but a full model based on experimental structures is lacking. Here, the authors complete the model of the yeast Y complex with two nanobody-bound crystal structures, providing molecular insights into its flexibility and membrane anc...
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2020
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oai:doaj.org-article:f0fe30db2f3249699674892162af134e2021-12-02T14:40:52ZYeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif10.1038/s41467-020-19885-52041-1723https://doaj.org/article/f0fe30db2f3249699674892162af134e2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19885-5https://doaj.org/toc/2041-1723The Y complex is an essential component of the nuclear pore complex but a full model based on experimental structures is lacking. Here, the authors complete the model of the yeast Y complex with two nanobody-bound crystal structures, providing molecular insights into its flexibility and membrane anchoring.Sarah A. NordeenDaniel L. TurmanThomas U. SchwartzNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
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Science Q Sarah A. Nordeen Daniel L. Turman Thomas U. Schwartz Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif |
description |
The Y complex is an essential component of the nuclear pore complex but a full model based on experimental structures is lacking. Here, the authors complete the model of the yeast Y complex with two nanobody-bound crystal structures, providing molecular insights into its flexibility and membrane anchoring. |
format |
article |
author |
Sarah A. Nordeen Daniel L. Turman Thomas U. Schwartz |
author_facet |
Sarah A. Nordeen Daniel L. Turman Thomas U. Schwartz |
author_sort |
Sarah A. Nordeen |
title |
Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif |
title_short |
Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif |
title_full |
Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif |
title_fullStr |
Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif |
title_full_unstemmed |
Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif |
title_sort |
yeast nup84-nup133 complex structure details flexibility and reveals conservation of the membrane anchoring alps motif |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/f0fe30db2f3249699674892162af134e |
work_keys_str_mv |
AT sarahanordeen yeastnup84nup133complexstructuredetailsflexibilityandrevealsconservationofthemembraneanchoringalpsmotif AT daniellturman yeastnup84nup133complexstructuredetailsflexibilityandrevealsconservationofthemembraneanchoringalpsmotif AT thomasuschwartz yeastnup84nup133complexstructuredetailsflexibilityandrevealsconservationofthemembraneanchoringalpsmotif |
_version_ |
1718390145904803840 |