Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture.
<h4>Background</h4>The cytokines TNF (TNFSF2) and IFNγ are important mediators of inflammatory bowel diseases and contribute to enhanced intestinal epithelial permeability by stimulating apoptosis and/or disrupting tight junctions. Apoptosis and tight junctions are also important for epi...
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Autores principales: | Kati Juuti-Uusitalo, Leon J Klunder, Klaas A Sjollema, Katarina Mackovicova, Ryuichi Ohgaki, Dick Hoekstra, Jan Dekker, Sven C D van Ijzendoorn |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/f0fff36a3114460bae10423387651c0b |
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