Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis.

Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis.

<h4>Background/aims</h4>Treatment with antiviral neuraminidase inhibitors suppresses influenza viral replication and antigen production, resulting in marked attenuation of mucosal immunity and mild suppression of systemic immunity in mice. This study investigated the effects of immunomod...

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Main Authors: Wakako Shinahara, Etsuhisa Takahashi, Takako Sawabuchi, Masaru Arai, Nobuo Hirotsu, Yoshio Takasaki, Shizuo Shindo, Kyoko Shibao, Takashi Yokoyama, Kiyoshi Nishikawa, Masahiro Mino, Minako Iwaya, Yuji Yamashita, Satoshi Suzuki, Dai Mizuno, Hiroshi Kido
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/f107e3b375a34d86b01d2cd359afb8d5
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