Chaperone addiction of toxin–antitoxin systems
Some bacterial toxin-antitoxin systems consist of a labile antitoxin that inhibits a toxin, and a chaperone that stabilizes the antitoxin. Here, Bordes et al. identify a sequence within the antitoxin to which the chaperone binds and which can be transferred to other proteins to make them chaperone-d...
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Nature Portfolio
2016
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oai:doaj.org-article:f1097791d71b44849d1f858666413acb2021-12-02T16:57:04ZChaperone addiction of toxin–antitoxin systems10.1038/ncomms133392041-1723https://doaj.org/article/f1097791d71b44849d1f858666413acb2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13339https://doaj.org/toc/2041-1723Some bacterial toxin-antitoxin systems consist of a labile antitoxin that inhibits a toxin, and a chaperone that stabilizes the antitoxin. Here, Bordes et al. identify a sequence within the antitoxin to which the chaperone binds and which can be transferred to other proteins to make them chaperone-dependent.Patricia BordesAmbre Julie SalaSara AyalaPauline TexierNawel SlamaAnne-Marie CirinesiValérie GuilletLionel MoureyPierre GenevauxNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q Patricia Bordes Ambre Julie Sala Sara Ayala Pauline Texier Nawel Slama Anne-Marie Cirinesi Valérie Guillet Lionel Mourey Pierre Genevaux Chaperone addiction of toxin–antitoxin systems |
description |
Some bacterial toxin-antitoxin systems consist of a labile antitoxin that inhibits a toxin, and a chaperone that stabilizes the antitoxin. Here, Bordes et al. identify a sequence within the antitoxin to which the chaperone binds and which can be transferred to other proteins to make them chaperone-dependent. |
format |
article |
author |
Patricia Bordes Ambre Julie Sala Sara Ayala Pauline Texier Nawel Slama Anne-Marie Cirinesi Valérie Guillet Lionel Mourey Pierre Genevaux |
author_facet |
Patricia Bordes Ambre Julie Sala Sara Ayala Pauline Texier Nawel Slama Anne-Marie Cirinesi Valérie Guillet Lionel Mourey Pierre Genevaux |
author_sort |
Patricia Bordes |
title |
Chaperone addiction of toxin–antitoxin systems |
title_short |
Chaperone addiction of toxin–antitoxin systems |
title_full |
Chaperone addiction of toxin–antitoxin systems |
title_fullStr |
Chaperone addiction of toxin–antitoxin systems |
title_full_unstemmed |
Chaperone addiction of toxin–antitoxin systems |
title_sort |
chaperone addiction of toxin–antitoxin systems |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/f1097791d71b44849d1f858666413acb |
work_keys_str_mv |
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1718382657211990016 |