The 5′ Untranslated Region of the <italic toggle="yes">EFG1</italic> Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in <italic toggle="yes">Candida albicans</italic>

The 5′ Untranslated Region of the <italic toggle="yes">EFG1</italic> Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in <italic toggle="yes">Candida albicans</italic>

ABSTRACT Extensive 5′ untranslated regions (UTR) are a hallmark of transcripts determining hyphal morphogenesis in Candida albicans. The major transcripts of the EFG1 gene, which are responsible for cellular morphogenesis and metabolism, contain a 5′ UTR of up to 1,170 nucleotides (nt). Deletion ana...

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Autores principales: Prashant R. Desai, Klaus Lengeler, Mario Kapitan, Silas Matthias Janßen, Paula Alepuz, Ilse D. Jacobsen, Joachim F. Ernst
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
5′ UTR
Candida albicans
EFG1
filamentation
hyphal morphogenesis
posttranscriptional regulation
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/f117cc8e47d443b4b75f19d70c67bdbb
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