Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy
Photodynamic therapy (PDT) is a low invasive antitumor therapy with fewer side effects. On the other hand, immunotherapy also has significant clinical applications in the treatment of cancer. Both therapies, on their own, have some limitations and are incapable of meeting the demands of the current...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:f11e09230e094020a01d8b511ade95362021-11-17T04:44:37ZCurrent Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy2234-943X10.3389/fonc.2021.738323https://doaj.org/article/f11e09230e094020a01d8b511ade95362021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.738323/fullhttps://doaj.org/toc/2234-943XPhotodynamic therapy (PDT) is a low invasive antitumor therapy with fewer side effects. On the other hand, immunotherapy also has significant clinical applications in the treatment of cancer. Both therapies, on their own, have some limitations and are incapable of meeting the demands of the current cancer treatment. The efficacy of PDT and immunotherapy against tumor metastasis and tumor recurrence may be improved by combination strategies. In this review, we discussed the possibility that PDT could be used to activate immune responses by inducing immunogenic cell death or generating cancer vaccines. Furthermore, we explored the latest advances in PDT antitumor therapy in combination with some immunotherapy such as immune adjuvants, inhibitors of immune suppression, and immune checkpoint blockade.Jianfeng HuaPan WuLu GanZhikun ZhangJian HeLiping ZhongYongxiang ZhaoYong HuangYong HuangFrontiers Media S.A.articlephotodynamic therapyimmunotherapycombinationtumornanoparticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021) |
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photodynamic therapy immunotherapy combination tumor nanoparticle Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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photodynamic therapy immunotherapy combination tumor nanoparticle Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Jianfeng Hua Pan Wu Lu Gan Zhikun Zhang Jian He Liping Zhong Yongxiang Zhao Yong Huang Yong Huang Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy |
description |
Photodynamic therapy (PDT) is a low invasive antitumor therapy with fewer side effects. On the other hand, immunotherapy also has significant clinical applications in the treatment of cancer. Both therapies, on their own, have some limitations and are incapable of meeting the demands of the current cancer treatment. The efficacy of PDT and immunotherapy against tumor metastasis and tumor recurrence may be improved by combination strategies. In this review, we discussed the possibility that PDT could be used to activate immune responses by inducing immunogenic cell death or generating cancer vaccines. Furthermore, we explored the latest advances in PDT antitumor therapy in combination with some immunotherapy such as immune adjuvants, inhibitors of immune suppression, and immune checkpoint blockade. |
format |
article |
author |
Jianfeng Hua Pan Wu Lu Gan Zhikun Zhang Jian He Liping Zhong Yongxiang Zhao Yong Huang Yong Huang |
author_facet |
Jianfeng Hua Pan Wu Lu Gan Zhikun Zhang Jian He Liping Zhong Yongxiang Zhao Yong Huang Yong Huang |
author_sort |
Jianfeng Hua |
title |
Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy |
title_short |
Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy |
title_full |
Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy |
title_fullStr |
Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy |
title_full_unstemmed |
Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy |
title_sort |
current strategies for tumor photodynamic therapy combined with immunotherapy |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/f11e09230e094020a01d8b511ade9536 |
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