Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy

Photodynamic therapy (PDT) is a low invasive antitumor therapy with fewer side effects. On the other hand, immunotherapy also has significant clinical applications in the treatment of cancer. Both therapies, on their own, have some limitations and are incapable of meeting the demands of the current...

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Autores principales: Jianfeng Hua, Pan Wu, Lu Gan, Zhikun Zhang, Jian He, Liping Zhong, Yongxiang Zhao, Yong Huang
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/f11e09230e094020a01d8b511ade9536
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spelling oai:doaj.org-article:f11e09230e094020a01d8b511ade95362021-11-17T04:44:37ZCurrent Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy2234-943X10.3389/fonc.2021.738323https://doaj.org/article/f11e09230e094020a01d8b511ade95362021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.738323/fullhttps://doaj.org/toc/2234-943XPhotodynamic therapy (PDT) is a low invasive antitumor therapy with fewer side effects. On the other hand, immunotherapy also has significant clinical applications in the treatment of cancer. Both therapies, on their own, have some limitations and are incapable of meeting the demands of the current cancer treatment. The efficacy of PDT and immunotherapy against tumor metastasis and tumor recurrence may be improved by combination strategies. In this review, we discussed the possibility that PDT could be used to activate immune responses by inducing immunogenic cell death or generating cancer vaccines. Furthermore, we explored the latest advances in PDT antitumor therapy in combination with some immunotherapy such as immune adjuvants, inhibitors of immune suppression, and immune checkpoint blockade.Jianfeng HuaPan WuLu GanZhikun ZhangJian HeLiping ZhongYongxiang ZhaoYong HuangYong HuangFrontiers Media S.A.articlephotodynamic therapyimmunotherapycombinationtumornanoparticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution DOAJ
collection DOAJ
language EN
topic photodynamic therapy
immunotherapy
combination
tumor
nanoparticle
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle photodynamic therapy
immunotherapy
combination
tumor
nanoparticle
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Jianfeng Hua
Pan Wu
Lu Gan
Zhikun Zhang
Jian He
Liping Zhong
Yongxiang Zhao
Yong Huang
Yong Huang
Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy
description Photodynamic therapy (PDT) is a low invasive antitumor therapy with fewer side effects. On the other hand, immunotherapy also has significant clinical applications in the treatment of cancer. Both therapies, on their own, have some limitations and are incapable of meeting the demands of the current cancer treatment. The efficacy of PDT and immunotherapy against tumor metastasis and tumor recurrence may be improved by combination strategies. In this review, we discussed the possibility that PDT could be used to activate immune responses by inducing immunogenic cell death or generating cancer vaccines. Furthermore, we explored the latest advances in PDT antitumor therapy in combination with some immunotherapy such as immune adjuvants, inhibitors of immune suppression, and immune checkpoint blockade.
format article
author Jianfeng Hua
Pan Wu
Lu Gan
Zhikun Zhang
Jian He
Liping Zhong
Yongxiang Zhao
Yong Huang
Yong Huang
author_facet Jianfeng Hua
Pan Wu
Lu Gan
Zhikun Zhang
Jian He
Liping Zhong
Yongxiang Zhao
Yong Huang
Yong Huang
author_sort Jianfeng Hua
title Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy
title_short Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy
title_full Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy
title_fullStr Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy
title_full_unstemmed Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy
title_sort current strategies for tumor photodynamic therapy combined with immunotherapy
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/f11e09230e094020a01d8b511ade9536
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