The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria

Anita R Shirodkar, Harry W Flynn Jr, Kyle Alliman, Geeta A Lalwani, Chrisfouad Alabiad, Andrew A Moshfeghi, Darlene MillerDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAPurpose: To identify patients who developed acute-onset end...

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Autores principales:	Anita R Shirodkar, Harry W Flynn Jr, Kyle Alliman, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f126fc28bcc44ddaa6e0e03650f74842
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spelling	oai:doaj.org-article:f126fc28bcc44ddaa6e0e03650f748422021-12-02T03:25:42ZThe comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria1177-54671177-5483https://doaj.org/article/f126fc28bcc44ddaa6e0e03650f748422010-04-01T00:00:00Zhttp://www.dovepress.com/the-comparison-of-clinical-outcomes-of-endophthalmitis-from-fluoroquin-a4227https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Anita R Shirodkar, Harry W Flynn Jr, Kyle Alliman, Geeta A Lalwani, Chrisfouad Alabiad, Andrew A Moshfeghi, Darlene MillerDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAPurpose: To identify patients who developed acute-onset endophthalmitis after clear corneal cataract surgery, and to compare treatment outcomes between cases caused by fluoroquinolone susceptible organisms versus fluoroquinolone resistant organisms.Design: Retrospective case series.Methods: Patients who developed endophthalmitis within six weeks of cataract surgery, and were treated between January 1996 and December 2008 at Bascom Palmer Eye Institute in Miami, Florida, were identified retrospectively. Clinical features, organisms cultured, and visual acuity outcomes were evaluated.Results: A total of 97 patients met study criteria, and 37 (38%) demonstrated in vitro fluoroquinolone resistance. All fluoroquinolone resistant endophthalmitis in the study was caused by either Staphylococcus epidermidis (n = 32) or Staphylococcus aureus (n = 5). Presenting clinical features were similar between fluoroquinolone resistant and fluoroquinolone susceptible groups. Final visual acuity was &ge;20/40 in 49% of fluoroquinolone-resistant cases and 42% of fluoroquinolonesusceptible cases. All fluoroquinolone-resistant isolates were susceptible to vancomycin.Conclusion: In the current study, approximately one-third of isolates were resistant to fluoroquinolones. There was no significant difference in clinical outcomes in this study, regardless of fluoroquinolone susceptibility.Keywords: endophthalmitis, fluoroquinolones Anita R ShirodkarHarry W Flynn JrKyle Allimanet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 211-214 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Anita R Shirodkar Harry W Flynn Jr Kyle Alliman et al The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria
description	Anita R Shirodkar, Harry W Flynn Jr, Kyle Alliman, Geeta A Lalwani, Chrisfouad Alabiad, Andrew A Moshfeghi, Darlene MillerDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAPurpose: To identify patients who developed acute-onset endophthalmitis after clear corneal cataract surgery, and to compare treatment outcomes between cases caused by fluoroquinolone susceptible organisms versus fluoroquinolone resistant organisms.Design: Retrospective case series.Methods: Patients who developed endophthalmitis within six weeks of cataract surgery, and were treated between January 1996 and December 2008 at Bascom Palmer Eye Institute in Miami, Florida, were identified retrospectively. Clinical features, organisms cultured, and visual acuity outcomes were evaluated.Results: A total of 97 patients met study criteria, and 37 (38%) demonstrated in vitro fluoroquinolone resistance. All fluoroquinolone resistant endophthalmitis in the study was caused by either Staphylococcus epidermidis (n = 32) or Staphylococcus aureus (n = 5). Presenting clinical features were similar between fluoroquinolone resistant and fluoroquinolone susceptible groups. Final visual acuity was &ge;20/40 in 49% of fluoroquinolone-resistant cases and 42% of fluoroquinolonesusceptible cases. All fluoroquinolone-resistant isolates were susceptible to vancomycin.Conclusion: In the current study, approximately one-third of isolates were resistant to fluoroquinolones. There was no significant difference in clinical outcomes in this study, regardless of fluoroquinolone susceptibility.Keywords: endophthalmitis, fluoroquinolones
format	article
author	Anita R Shirodkar Harry W Flynn Jr Kyle Alliman et al
author_facet	Anita R Shirodkar Harry W Flynn Jr Kyle Alliman et al
author_sort	Anita R Shirodkar
title	The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria
title_short	The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria
title_full	The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria
title_fullStr	The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria
title_full_unstemmed	The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria
title_sort	comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/f126fc28bcc44ddaa6e0e03650f74842
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The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria

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