The regulatory light chain mediates inactivation of myosin motors during active shortening of cardiac muscle
Heart muscle cells are inactivated when they shorten during ejection, accelerating relaxation to facilitate refilling before the next beat. The authors propose that sequential folding of myosin motors onto the filament backbone may be responsible for shortening-induced de-activation in the heart.
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/f131c3dff37648908503f6f87fe24b43 |
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