Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials

This systematic review and meta-analysis on randomized controlled trials (RCTs) evaluated the impact of astaxanthin (AST) supplementation on blood pressure in adults. We conducted a comprehensive search using different electronic databases. Ten RCTs with 493 participants that reported the effect of...

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Autores principales:	Elahe Mokhtari, Sahar Rafiei, Nafiseh Shokri-Mashhadi, Parvane Saneei
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Astaxanthin Systolic blood pressure Diastolic blood pressure Randomized controlled trials Meta-analysis Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/f137e5c75ab441a595840832dfc396c0
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spelling	oai:doaj.org-article:f137e5c75ab441a595840832dfc396c02021-11-24T04:27:35ZImpact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials1756-464610.1016/j.jff.2021.104860https://doaj.org/article/f137e5c75ab441a595840832dfc396c02021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1756464621005090https://doaj.org/toc/1756-4646This systematic review and meta-analysis on randomized controlled trials (RCTs) evaluated the impact of astaxanthin (AST) supplementation on blood pressure in adults. We conducted a comprehensive search using different electronic databases. Ten RCTs with 493 participants that reported the effect of AST supplementation on blood pressure in adults were included. AST supplementation led to a marginally decline in diastolic blood pressure (DBP) (mean difference (MD) = −1.21; 95 %CI: −2.51, 0.09), but not systolic blood pressure. In patients, AST supplementation reduced DBP by 2.77 mmHg (95 %CI: −4.34, −1.19). Also, assigning ≥ 12 mg of AST to adults resulted in a slight decrease in DBP (MD = −0.89; 95 %CI: −1.82, 0.04). AST supplementation significantly reduced DBP by 2.27 mmHg in participants from Asian countries (95 %CI: −3.71, −0.83). This meta-analysis of RCTs disclosed that AST supplementation could reduce DBP, especially with a dose of ≥ 12 mg/d supplementation, in patient individuals and in participants from Asian countries.Elahe MokhtariSahar RafieiNafiseh Shokri-MashhadiParvane SaneeiElsevierarticleAstaxanthinSystolic blood pressureDiastolic blood pressureRandomized controlled trialsMeta-analysisNutrition. Foods and food supplyTX341-641ENJournal of Functional Foods, Vol 87, Iss , Pp 104860- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Astaxanthin Systolic blood pressure Diastolic blood pressure Randomized controlled trials Meta-analysis Nutrition. Foods and food supply TX341-641
spellingShingle	Astaxanthin Systolic blood pressure Diastolic blood pressure Randomized controlled trials Meta-analysis Nutrition. Foods and food supply TX341-641 Elahe Mokhtari Sahar Rafiei Nafiseh Shokri-Mashhadi Parvane Saneei Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials
description	This systematic review and meta-analysis on randomized controlled trials (RCTs) evaluated the impact of astaxanthin (AST) supplementation on blood pressure in adults. We conducted a comprehensive search using different electronic databases. Ten RCTs with 493 participants that reported the effect of AST supplementation on blood pressure in adults were included. AST supplementation led to a marginally decline in diastolic blood pressure (DBP) (mean difference (MD) = −1.21; 95 %CI: −2.51, 0.09), but not systolic blood pressure. In patients, AST supplementation reduced DBP by 2.77 mmHg (95 %CI: −4.34, −1.19). Also, assigning ≥ 12 mg of AST to adults resulted in a slight decrease in DBP (MD = −0.89; 95 %CI: −1.82, 0.04). AST supplementation significantly reduced DBP by 2.27 mmHg in participants from Asian countries (95 %CI: −3.71, −0.83). This meta-analysis of RCTs disclosed that AST supplementation could reduce DBP, especially with a dose of ≥ 12 mg/d supplementation, in patient individuals and in participants from Asian countries.
format	article
author	Elahe Mokhtari Sahar Rafiei Nafiseh Shokri-Mashhadi Parvane Saneei
author_facet	Elahe Mokhtari Sahar Rafiei Nafiseh Shokri-Mashhadi Parvane Saneei
author_sort	Elahe Mokhtari
title	Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials
title_short	Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials
title_full	Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials
title_fullStr	Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials
title_full_unstemmed	Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials
title_sort	impact of astaxanthin supplementation on blood pressure: a systematic review and meta-analysis of randomized controlled trials
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/f137e5c75ab441a595840832dfc396c0
work_keys_str_mv	AT elahemokhtari impactofastaxanthinsupplementationonbloodpressureasystematicreviewandmetaanalysisofrandomizedcontrolledtrials AT saharrafiei impactofastaxanthinsupplementationonbloodpressureasystematicreviewandmetaanalysisofrandomizedcontrolledtrials AT nafisehshokrimashhadi impactofastaxanthinsupplementationonbloodpressureasystematicreviewandmetaanalysisofrandomizedcontrolledtrials AT parvanesaneei impactofastaxanthinsupplementationonbloodpressureasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
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Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials

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