The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis

Abstract The aim of this study was to investigate the clinical efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis in adult patients. A retrospective analysis was conducted between June 2013 and September 2017of 88 adult patie...

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Autores principales:	Zhi Yi, Qichun Song, Jiao Zhou, Yongchun Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f1433fd8713e4ca9b1d5e0016a3e6bc5
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spelling	oai:doaj.org-article:f1433fd8713e4ca9b1d5e0016a3e6bc52021-12-02T13:30:28ZThe efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis10.1038/s41598-021-83178-02045-2322https://doaj.org/article/f1433fd8713e4ca9b1d5e0016a3e6bc52021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-83178-0https://doaj.org/toc/2045-2322Abstract The aim of this study was to investigate the clinical efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis in adult patients. A retrospective analysis was conducted between June 2013 and September 2017of 88 adult patients with thoracic spinal tuberculosis. All patients were treated with single posterior debridement, bone grafting and instrumentation. The clinical manifestations and laboratory and imageological results were subsequently analysed. All patients were followed for 40.6 ± 4.1 months (range, 36–48 m). Bony fusion was achieved in all bone grafts of thoracic vertebrae. The visual analogue scale scores, erythrocyte sedimentation rate and C-reactive protein levels 6 weeks after surgery and at the final follow up were significantly lower than the preoperative levels (P < 0.05). The postoperative and final follow up kyphosis angles were both significantly smaller than the preoperative kyphosis angles (P < 0.05). The postoperative angle correction rate reached 81.5% and the postoperative angle loss reached only 4.1%. At the last follow up, American Spinal Injury Association improvement was significant, compared with the preoperative levels (P < 0.05). The single posterior approach can achieve satisfactory clinical outcomes in the treatment of thoracic spinal tuberculosis.Zhi YiQichun SongJiao ZhouYongchun ZhouNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Zhi Yi Qichun Song Jiao Zhou Yongchun Zhou The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis
description	Abstract The aim of this study was to investigate the clinical efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis in adult patients. A retrospective analysis was conducted between June 2013 and September 2017of 88 adult patients with thoracic spinal tuberculosis. All patients were treated with single posterior debridement, bone grafting and instrumentation. The clinical manifestations and laboratory and imageological results were subsequently analysed. All patients were followed for 40.6 ± 4.1 months (range, 36–48 m). Bony fusion was achieved in all bone grafts of thoracic vertebrae. The visual analogue scale scores, erythrocyte sedimentation rate and C-reactive protein levels 6 weeks after surgery and at the final follow up were significantly lower than the preoperative levels (P < 0.05). The postoperative and final follow up kyphosis angles were both significantly smaller than the preoperative kyphosis angles (P < 0.05). The postoperative angle correction rate reached 81.5% and the postoperative angle loss reached only 4.1%. At the last follow up, American Spinal Injury Association improvement was significant, compared with the preoperative levels (P < 0.05). The single posterior approach can achieve satisfactory clinical outcomes in the treatment of thoracic spinal tuberculosis.
format	article
author	Zhi Yi Qichun Song Jiao Zhou Yongchun Zhou
author_facet	Zhi Yi Qichun Song Jiao Zhou Yongchun Zhou
author_sort	Zhi Yi
title	The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis
title_short	The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis
title_full	The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis
title_fullStr	The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis
title_full_unstemmed	The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis
title_sort	efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f1433fd8713e4ca9b1d5e0016a3e6bc5
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The efficacy of single posterior debridement, bone grafting and instrumentation for the treatment of thoracic spinal tuberculosis

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