Power determination in vitamin D randomised control trials and characterising factors affecting it through a novel simulation-based tool
Abstract Thousands of observational studies have linked vitamin D deficiency with numerous diseases, but randomised controlled trials (RCTs) often fail to show benefit of supplementation. Population characteristics and trial design have long been suspected to undermine power but were not systematica...
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Autores principales: | Jason Wyse, Rebecca Mangan, Lina Zgaga |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/f1447639aae740ffbcac08cbd92a0e33 |
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