Digital microfluidic isolation of single cells for -Omics

Multi-Omic approaches are a powerful way for obtaining in-depth understanding of a cell’s state. Here the authors present DISCO, combining digital microfluidics, laser cell lysis, and artificial intelligence-driven image processing to analyze single-cell genomes, transcriptomes and proteomes in a mi...

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Autores principales:	Julian Lamanna, Erica Y. Scott, Harrison S. Edwards, M. Dean Chamberlain, Michael D. M. Dryden, Jiaxi Peng, Barbara Mair, Adam Lee, Calvin Chan, Alexandros A. Sklavounos, Austin Heffernan, Farhana Abbas, Charis Lam, Maxwell E. Olson, Jason Moffat, Aaron R. Wheeler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f14d36deac8249f8ad452834eda79d88
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spelling	oai:doaj.org-article:f14d36deac8249f8ad452834eda79d882021-12-02T14:42:14ZDigital microfluidic isolation of single cells for -Omics10.1038/s41467-020-19394-52041-1723https://doaj.org/article/f14d36deac8249f8ad452834eda79d882020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19394-5https://doaj.org/toc/2041-1723Multi-Omic approaches are a powerful way for obtaining in-depth understanding of a cell’s state. Here the authors present DISCO, combining digital microfluidics, laser cell lysis, and artificial intelligence-driven image processing to analyze single-cell genomes, transcriptomes and proteomes in a mixed population.Julian LamannaErica Y. ScottHarrison S. EdwardsM. Dean ChamberlainMichael D. M. DrydenJiaxi PengBarbara MairAdam LeeCalvin ChanAlexandros A. SklavounosAustin HeffernanFarhana AbbasCharis LamMaxwell E. OlsonJason MoffatAaron R. WheelerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julian Lamanna Erica Y. Scott Harrison S. Edwards M. Dean Chamberlain Michael D. M. Dryden Jiaxi Peng Barbara Mair Adam Lee Calvin Chan Alexandros A. Sklavounos Austin Heffernan Farhana Abbas Charis Lam Maxwell E. Olson Jason Moffat Aaron R. Wheeler Digital microfluidic isolation of single cells for -Omics
description	Multi-Omic approaches are a powerful way for obtaining in-depth understanding of a cell’s state. Here the authors present DISCO, combining digital microfluidics, laser cell lysis, and artificial intelligence-driven image processing to analyze single-cell genomes, transcriptomes and proteomes in a mixed population.
format	article
author	Julian Lamanna Erica Y. Scott Harrison S. Edwards M. Dean Chamberlain Michael D. M. Dryden Jiaxi Peng Barbara Mair Adam Lee Calvin Chan Alexandros A. Sklavounos Austin Heffernan Farhana Abbas Charis Lam Maxwell E. Olson Jason Moffat Aaron R. Wheeler
author_facet	Julian Lamanna Erica Y. Scott Harrison S. Edwards M. Dean Chamberlain Michael D. M. Dryden Jiaxi Peng Barbara Mair Adam Lee Calvin Chan Alexandros A. Sklavounos Austin Heffernan Farhana Abbas Charis Lam Maxwell E. Olson Jason Moffat Aaron R. Wheeler
author_sort	Julian Lamanna
title	Digital microfluidic isolation of single cells for -Omics
title_short	Digital microfluidic isolation of single cells for -Omics
title_full	Digital microfluidic isolation of single cells for -Omics
title_fullStr	Digital microfluidic isolation of single cells for -Omics
title_full_unstemmed	Digital microfluidic isolation of single cells for -Omics
title_sort	digital microfluidic isolation of single cells for -omics
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f14d36deac8249f8ad452834eda79d88
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Digital microfluidic isolation of single cells for -Omics

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