Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteris...
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2018
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oai:doaj.org-article:f15fa41a1567456bbadf5b59246f8cd72021-12-02T16:56:37ZBroad phylogenetic analysis of cation/proton antiporters reveals transport determinants10.1038/s41467-018-06770-52041-1723https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd72018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06770-5https://doaj.org/toc/2041-1723Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteristics.Gal MasratiManish DwivediAbraham RimonYael Gluck-MargolinAmit KesselHaim AshkenazyItay MayroseEtana PadanNir Ben-TalNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Gal Masrati Manish Dwivedi Abraham Rimon Yael Gluck-Margolin Amit Kessel Haim Ashkenazy Itay Mayrose Etana Padan Nir Ben-Tal Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
description |
Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteristics. |
format |
article |
author |
Gal Masrati Manish Dwivedi Abraham Rimon Yael Gluck-Margolin Amit Kessel Haim Ashkenazy Itay Mayrose Etana Padan Nir Ben-Tal |
author_facet |
Gal Masrati Manish Dwivedi Abraham Rimon Yael Gluck-Margolin Amit Kessel Haim Ashkenazy Itay Mayrose Etana Padan Nir Ben-Tal |
author_sort |
Gal Masrati |
title |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
title_short |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
title_full |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
title_fullStr |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
title_full_unstemmed |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
title_sort |
broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd7 |
work_keys_str_mv |
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1718382775459905536 |