Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants

Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteris...

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Autores principales: Gal Masrati, Manish Dwivedi, Abraham Rimon, Yael Gluck-Margolin, Amit Kessel, Haim Ashkenazy, Itay Mayrose, Etana Padan, Nir Ben-Tal
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd7
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spelling oai:doaj.org-article:f15fa41a1567456bbadf5b59246f8cd72021-12-02T16:56:37ZBroad phylogenetic analysis of cation/proton antiporters reveals transport determinants10.1038/s41467-018-06770-52041-1723https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd72018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06770-5https://doaj.org/toc/2041-1723Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteristics.Gal MasratiManish DwivediAbraham RimonYael Gluck-MargolinAmit KesselHaim AshkenazyItay MayroseEtana PadanNir Ben-TalNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gal Masrati
Manish Dwivedi
Abraham Rimon
Yael Gluck-Margolin
Amit Kessel
Haim Ashkenazy
Itay Mayrose
Etana Padan
Nir Ben-Tal
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
description Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteristics.
format article
author Gal Masrati
Manish Dwivedi
Abraham Rimon
Yael Gluck-Margolin
Amit Kessel
Haim Ashkenazy
Itay Mayrose
Etana Padan
Nir Ben-Tal
author_facet Gal Masrati
Manish Dwivedi
Abraham Rimon
Yael Gluck-Margolin
Amit Kessel
Haim Ashkenazy
Itay Mayrose
Etana Padan
Nir Ben-Tal
author_sort Gal Masrati
title Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
title_short Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
title_full Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
title_fullStr Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
title_full_unstemmed Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
title_sort broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd7
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